Basic Information
ID: ALA4476981
Type: Binding
Description: Inhibition of recombinant His6-tagged MAT2A (unknown origin) expressed in SF9 insect cells using L-Met as substrate preincubated for 60 mins followed by substrate and ATP addition and measured after 60 mins by spectrophotometric analysis
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4476981
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.47 | 6.08 | 6.08 |
| 434.50 | 5.36 | 5.36 |
| 435.53 | 5.20 | 5.20 |
| 422.49 | 4.49 | 4.49 |
| 458.52 | 5.89 | 5.89 |
| 496.53 | 6.30 | 6.30 |
| 446.49 | 6.02 | 6.02 |
| 526.56 | 5.21 | 5.21 |
| 489.58 | 6.46 | 6.46 |
| 460.50 | 5.20 | 5.20 |
| 421.50 | 5.59 | 5.59 |
| 519.99 | 6.82 | 6.82 |
| 520.98 | 6.22 | 6.22 |
| 396.45 | 4.67 | 4.67 |
| 395.46 | 4.80 | 4.80 |
| 428.54 | 4.67 | 4.67 |
| 477.46 | 5.09 | 5.09 |
| 473.49 | 5.79 | 5.79 |
| 423.47 | 4.75 | 4.75 |
| 488.55 | 5.51 | 5.51 |
| 462.94 | 6.53 | 6.53 |
| 415.50 | 4.06 | 4.06 |
| 502.54 | 4.54 | 4.54 |
| 510.60 | 7.00 | 7.00 |
| 515.58 | 5.73 | 5.73 |
| 475.51 | 5.76 | 5.76 |
| 537.58 | 5.22 | 5.22 |
| 492.58 | 5.49 | 5.49 |
| 429.48 | 5.28 | 5.28 |
| 475.51 | 5.76 | 5.76 |
| 444.49 | 5.06 | 5.06 |
| 499.58 | 6.33 | 6.33 |
| 401.47 | 3.34 | 3.34 |
| 471.52 | 4.93 | 4.93 |
| 384.48 | 4.66 | 4.66 |
| 506.59 | 5.66 | 5.66 |
| 510.56 | 6.04 | 6.04 |
| 385.47 | 4.05 | 4.05 |
| 502.53 | 5.27 | 5.27 |
| 503.54 | 6.31 | 6.31 |
| 486.54 | 5.57 | 5.57 |
| 492.56 | 5.63 | 5.63 |
| 457.48 | 5.06 | 5.06 |
| 394.43 | 4.31 | 4.31 |
| 491.56 | 5.25 | 5.25 |
| 462.94 | 6.53 | 6.53 |
| 399.50 | 4.24 | 4.24 |
| 490.57 | 5.86 | 5.86 |
| 530.54 | 6.08 | 6.08 |
| 480.57 | 4.98 | 4.98 |
| 448.53 | 5.14 | 5.14 |
| 505.58 | 5.44 | 5.44 |
| 484.56 | 6.78 | 6.78 |
| 441.54 | 4.61 | 4.61 |
| 506.57 | 4.83 | 4.83 |
| 412.49 | 4.48 | 4.48 |
| 568.60 | 5.45 | 5.45 |
| 475.51 | 5.76 | 5.76 |
| 391.50 | 4.11 | 4.11 |
| 433.52 | 5.57 | 5.57 |
| 450.49 | 4.91 | 4.91 |
| 511.55 | 5.44 | 5.44 |
| 509.57 | 6.35 | 6.35 |
| 443.51 | 5.03 | 5.03 |
| 501.55 | 5.88 | 5.88 |
| 418.46 | 4.60 | 4.60 |
| 457.54 | 5.00 | 5.00 |
| 491.58 | 6.23 | 6.23 |
| 489.54 | 4.76 | 4.76 |
| 501.55 | 5.15 | 5.15 |
| 462.58 | 4.06 | 4.06 |
| 463.57 | 5.40 | 5.40 |
| 491.51 | 4.74 | 4.74 |
| 491.58 | 6.23 | 6.23 |
| 472.50 | 5.58 | 5.58 |
| 526.56 | 4.62 | 4.62 |
| 487.52 | 4.96 | 4.96 |
| 450.50 | 4.25 | 4.25 |
| 487.52 | 5.61 | 5.61 |
| 448.53 | 5.35 | 5.35 |
| 489.58 | 6.46 | 6.46 |
| 491.56 | 5.25 | 5.25 |
| 474.52 | 5.50 | 5.50 |
| 459.51 | 5.28 | 5.28 |
| 374.45 | 3.38 | 3.38 |
| 399.50 | 4.24 | 4.24 |
| 463.93 | 5.93 | 5.93 |
| 501.55 | 5.88 | 5.88 |
| 437.50 | 4.53 | 4.53 |
| 413.48 | 4.48 | 4.48 |
| 453.50 | 4.41 | 4.41 |
| 409.45 | 4.74 | 4.74 |
| 395.42 | 4.43 | 4.43 |
| 510.56 | 6.04 | 6.04 |
| 497.56 | 5.92 | 5.92 |
| 444.49 | 5.59 | 5.59 |
| 475.51 | 4.89 | 4.89 |
| 501.55 | 5.99 | 5.99 |
| 526.56 | 4.62 | 4.62 |
| 429.48 | 5.28 | 5.28 |
| 510.56 | 4.73 | 4.73 |
| 376.50 | 4.65 | 4.65 |
| 442.52 | 5.89 | 5.89 |
| 501.55 | 4.18 | 4.18 |
| 454.53 | 4.54 | 4.54 |
| 461.49 | 4.59 | 4.59 |
| 430.47 | 5.28 | 5.28 |
| 512.57 | 5.97 | 5.97 |
| 507.56 | 6.11 | 6.11 |
| 424.51 | 4.53 | 4.53 |
| 421.50 | 5.73 | 5.73 |
| 413.48 | 5.03 | 5.03 |
| 485.55 | 5.92 | 5.92 |
| 452.51 | 4.44 | 4.44 |
| 485.55 | 5.21 | 5.21 |
| 466.50 | 4.15 | 4.15 |
| 418.50 | 5.78 | 5.78 |
| 428.50 | 5.88 | 5.88 |
| 414.47 | 5.57 | 5.57 |
| 512.57 | 5.10 | 5.10 |
| 569.58 | 5.88 | 5.88 |
| 448.53 | 4.72 | 4.72 |
| 486.54 | 4.74 | 4.74 |
| 443.51 | 5.46 | 5.46 |
| 478.55 | 4.80 | 4.80 |
| 516.56 | 5.57 | 5.57 |
| 485.55 | 6.17 | 6.17 |
| 429.48 | 5.28 | 5.28 |
| 519.99 | 6.82 | 6.82 |
| 435.48 | 5.10 | 5.10 |
| 486.54 | 5.57 | 5.57 |
| 493.59 | 5.55 | 5.55 |
| 563.64 | 6.41 | 6.41 |
| 485.54 | 6.82 | 6.82 |
| 475.51 | 4.07 | 4.07 |
| 411.51 | 5.63 | 5.63 |
| 478.56 | 5.79 | 5.79 |
| 528.57 | 5.27 | 5.27 |
| 501.55 | 5.15 | 5.15 |
| 474.52 | 5.50 | 5.50 |
| 506.59 | 5.94 | 5.94 |
| 486.54 | 5.57 | 5.57 |
| 502.53 | 5.27 | 5.27 |
| 434.50 | 5.14 | 5.14 |
| 449.51 | 4.75 | 4.75 |
| 400.48 | 4.36 | 4.36 |
| 504.55 | 5.51 | 5.51 |
| 432.48 | 5.10 | 5.10 |
| 434.54 | 6.26 | 6.26 |
| 393.49 | 2.82 | 2.82 |
| 490.57 | 5.86 | 5.86 |
| 413.50 | 5.11 | 5.11 |
| 401.47 | 3.76 | 3.76 |
| 468.51 | 6.42 | 6.42 |
| 459.51 | 5.28 | 5.28 |
| 511.55 | 5.44 | 5.44 |
| 503.52 | 4.67 | 4.67 |
| 447.54 | 5.32 | 5.32 |
| 441.53 | 4.83 | 4.83 |
| 603.68 | 5.46 | 5.46 |
| 526.60 | 5.99 | 5.99 |
| 496.60 | 5.92 | 5.92 |
| 500.56 | 6.59 | 6.59 |
| 496.61 | 5.51 | 5.51 |
| 408.46 | 4.74 | 4.74 |
| 524.58 | 6.65 | 6.65 |
| 427.51 | 3.75 | 3.75 |
| 423.47 | 5.05 | 5.05 |
| 485.55 | 6.17 | 6.17 |
| 436.47 | 4.13 | 4.13 |
| 413.48 | 4.48 | 4.48 |
| 521.62 | 4.63 | 4.63 |
| 516.56 | 5.57 | 5.57 |
| 407.52 | 2.95 | 2.95 |
| 507.58 | 5.21 | 5.21 |
| 503.54 | 6.31 | 6.31 |
| 496.60 | 5.92 | 5.92 |
| 408.46 | 4.19 | 4.19 |
| 348.45 | 3.87 | 3.87 |
| 431.50 | 5.22 | 5.22 |
| 446.46 | 4.16 | 4.16 |
| 444.50 | 4.86 | 4.86 |
| 417.47 | 5.21 | 5.21 |
| 501.55 | 4.29 | 4.29 |
| 489.58 | 6.46 | 6.46 |
| 486.54 | 5.57 | 5.57 |
| 407.47 | 5.34 | 5.34 |
| 475.51 | 4.07 | 4.07 |
| 471.51 | 5.45 | 5.45 |
| 458.52 | 5.07 | 5.07 |
| 508.56 | 5.33 | 5.33 |
| 511.59 | 6.40 | 6.40 |
| 457.54 | 5.29 | 5.29 |
| 486.54 | 5.57 | 5.57 |
| 455.56 | 5.71 | 5.71 |
| 429.48 | 5.28 | 5.28 |
| 455.51 | 4.58 | 4.58 |
| 397.48 | 4.59 | 4.59 |
| 487.52 | 4.96 | 4.96 |
| 491.56 | 5.25 | 5.25 |
| 397.48 | 5.33 | 5.33 |
| 539.52 | 5.75 | 5.75 |
| 474.52 | 5.50 | 5.50 |
| 495.55 | 5.28 | 5.28 |
| 458.52 | 5.89 | 5.89 |
| 500.57 | 5.72 | 5.72 |
| 486.54 | 5.57 | 5.57 |
| 526.63 | 7.08 | 7.08 |
| 501.55 | 5.15 | 5.15 |
| 495.55 | 6.04 | 6.04 |
| 439.52 | 4.11 | 4.11 |
| 506.57 | 6.71 | 6.71 |
| 490.57 | 5.86 | 5.86 |
| 436.52 | 4.60 | 4.60 |
| 418.46 | 4.90 | 4.90 |
| 423.47 | 4.52 | 4.52 |
| 471.52 | 5.53 | 5.53 |
| 546.59 | 5.98 | 5.98 |
| 436.46 | 4.52 | 4.52 |
| 501.55 | 5.88 | 5.88 |
| 522.59 | 5.64 | 5.64 |
| 479.54 | 6.05 | 6.05 |
| 492.56 | 5.63 | 5.63 |
| 520.98 | 6.22 | 6.22 |
| 507.48 | 5.07 | 5.07 |
| 465.51 | 3.93 | 3.93 |
| 516.57 | 5.00 | 5.00 |
| 427.50 | 4.81 | 4.81 |
| 487.52 | 4.50 | 4.50 |
| 393.45 | 5.04 | 5.04 |
| 494.56 | 5.82 | 5.82 |
| 459.51 | 5.28 | 5.28 |
| 426.52 | 4.78 | 4.78 |
| 432.53 | 6.17 | 6.17 |
| 489.54 | 5.08 | 5.08 |
| 448.48 | 4.66 | 4.66 |
| 476.54 | 5.55 | 5.55 |
| 510.56 | 6.04 | 6.04 |
| 490.57 | 5.86 | 5.86 |
| 511.55 | 5.44 | 5.44 |
| 411.44 | 5.18 | 5.18 |
| 503.54 | 6.31 | 6.31 |
| 501.55 | 5.15 | 5.15 |
| 520.59 | 5.86 | 5.86 |
| 409.45 | 4.74 | 4.74 |
| 427.89 | 5.69 | 5.69 |