Basic Information
ID: ALA4476998
Type: Functional
Description: Antiproliferative activity against human NCI-H2171 cells after 72 hrs by ATPlite assay
Organism: Homo sapiens
Cell type: NCI-H2171
Activity Charts
Bioactivity
Activity Types for Assay ALA4476998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.53 | 4.75 | 4.75 |
| 329.45 | 3.63 | 3.63 |
| 477.66 | 5.06 | 5.06 |
| 531.71 | 5.38 | 5.38 |
| 494.69 | 4.64 | 4.64 |
| 524.72 | 4.59 | 4.59 |
| 524.72 | 4.59 | 4.59 |
| 524.68 | 6.53 | 6.53 |
| 585.78 | 3.81 | 3.81 |
| 523.68 | 4.31 | 4.31 |
| 370.50 | 2.83 | 2.83 |
| 523.68 | 4.31 | 4.31 |
| 512.62 | 5.20 | 5.20 |
| 476.67 | 6.23 | 6.23 |
| 501.68 | 3.37 | 3.37 |
| 456.68 | 5.51 | 5.51 |
| 536.68 | 4.63 | 4.63 |
| 549.72 | 4.86 | 4.86 |
| 426.61 | 4.18 | 4.18 |
| 507.69 | 4.61 | 4.61 |
| 430.60 | 3.54 | 3.54 |
| 535.58 | 6.27 | 6.27 |
| 585.78 | 3.81 | 3.81 |
| 537.71 | 4.70 | 4.70 |
| 462.62 | 4.32 | 4.32 |
| 385.51 | 3.98 | 3.98 |
| 581.74 | 4.74 | 4.74 |
| 357.50 | 4.58 | 4.58 |
| 495.67 | 5.27 | 5.27 |
| 561.73 | 5.39 | 5.39 |
| 494.65 | 3.69 | 3.69 |
| 371.53 | 4.40 | 4.40 |
| 510.69 | 3.94 | 3.94 |
| 537.71 | 4.70 | 4.70 |
| 438.58 | 3.51 | 3.51 |
| 524.72 | 4.59 | 4.59 |
| 590.82 | 4.65 | 4.65 |
| 521.71 | 5.25 | 5.25 |
| 448.59 | 3.94 | 3.94 |
| 414.60 | 4.34 | 4.34 |
| 539.56 | 4.18 | 4.18 |
| 507.69 | 4.86 | 4.86 |
| 427.60 | 4.61 | 4.61 |
| 500.69 | 5.24 | 5.24 |
| 521.71 | 5.25 | 5.25 |
| 399.58 | 5.70 | 5.70 |
| 563.75 | 4.60 | 4.60 |
| 480.66 | 4.40 | 4.40 |
| 509.66 | 3.27 | 3.27 |
| 482.60 | 5.41 | 5.41 |
| 655.50 | 6.11 | 6.11 |
| 670.65 | 3.88 | 3.88 |
| 543.72 | 5.45 | 5.45 |
| 550.71 | 4.26 | 4.26 |
| 434.59 | 5.03 | 5.03 |
| 414.53 | 3.08 | 3.08 |
| 477.66 | 5.06 | 5.06 |
| 468.69 | 5.65 | 5.65 |
| 430.60 | 3.62 | 3.62 |
| 446.67 | 4.72 | 4.72 |
| 507.69 | 4.61 | 4.61 |
| 414.60 | 4.39 | 4.39 |
| 572.76 | 5.15 | 5.15 |
| 414.56 | 2.99 | 2.99 |
| 506.70 | 5.67 | 5.67 |
| 492.67 | 5.94 | 5.94 |
| 397.45 | 4.65 | 4.65 |
| 536.68 | 4.63 | 4.63 |
| 585.78 | 3.81 | 3.81 |
| 373.46 | 3.36 | 3.36 |
| 456.64 | 4.65 | 4.65 |
| 496.66 | 3.73 | 3.73 |
| 372.52 | 3.69 | 3.69 |
| 497.69 | 3.61 | 3.61 |
| 494.66 | 6.37 | 6.37 |
| 482.64 | 3.63 | 3.63 |
| 440.64 | 4.83 | 4.83 |
| 524.68 | 6.53 | 6.53 |
| 385.56 | 5.31 | 5.31 |
| 547.71 | 4.40 | 4.40 |
| 603.86 | 4.50 | 4.50 |
| 458.61 | 3.79 | 3.79 |
| 524.72 | 4.25 | 4.25 |
| 430.60 | 3.62 | 3.62 |
| 521.71 | 5.25 | 5.25 |
| 517.68 | 4.77 | 4.77 |
| 495.47 | 4.00 | 4.00 |
| 444.58 | 3.70 | 3.70 |
| 531.71 | 5.08 | 5.08 |
| 520.68 | 4.64 | 4.64 |
| 444.63 | 4.18 | 4.18 |
| 343.48 | 3.94 | 3.94 |
| 483.71 | 4.37 | 4.37 |
| 537.71 | 4.61 | 4.61 |
| 402.55 | 2.58 | 2.58 |
| 527.12 | 5.56 | 5.56 |
| 389.52 | 5.22 | 5.22 |
| 494.69 | 4.71 | 4.71 |
| 570.76 | 4.31 | 4.31 |
| 551.69 | 4.08 | 4.08 |
| 483.62 | 3.89 | 3.89 |
| 343.48 | 3.94 | 3.94 |
| 531.71 | 5.08 | 5.08 |
| 532.70 | 4.78 | 4.78 |
| 694.87 | 3.16 | 3.16 |
| 500.76 | 6.03 | 6.03 |
| 618.83 | 4.29 | 4.29 |
| 537.71 | 4.61 | 4.61 |
| 585.78 | 4.27 | 4.27 |
| 428.63 | 4.41 | 4.41 |
| 571.75 | 3.55 | 3.55 |
| 581.74 | 4.74 | 4.74 |
| 499.75 | 5.05 | 5.05 |
| 428.63 | 4.95 | 4.95 |
| 428.63 | 4.73 | 4.73 |
| 560.67 | 5.92 | 5.92 |
| 519.74 | 6.18 | 6.18 |
| 507.69 | 4.61 | 4.61 |
| 563.71 | 4.23 | 4.23 |
| 442.65 | 5.34 | 5.34 |
| 508.67 | 4.61 | 4.61 |
| 507.69 | 4.61 | 4.61 |
| 492.67 | 5.37 | 5.37 |
| 526.66 | 4.75 | 4.75 |
| 576.67 | 4.90 | 4.90 |
| 398.56 | 3.75 | 3.75 |
| 472.68 | 4.96 | 4.96 |
| 414.60 | 4.34 | 4.34 |
| 428.63 | 4.95 | 4.95 |
| 507.69 | 4.61 | 4.61 |
| 523.68 | 4.31 | 4.31 |
| 466.64 | 4.39 | 4.39 |
| 456.68 | 5.37 | 5.37 |
| 386.55 | 3.56 | 3.56 |
| 590.82 | 4.65 | 4.65 |
| 444.63 | 3.80 | 3.80 |
| 384.51 | 3.53 | 3.53 |
| 483.62 | 3.89 | 3.89 |
| 553.71 | 4.31 | 4.31 |
| 463.63 | 4.23 | 4.23 |
| 448.59 | 3.76 | 3.76 |
| 550.71 | 4.26 | 4.26 |
| 357.50 | 4.58 | 4.58 |
| 507.69 | 4.61 | 4.61 |
| 406.54 | 4.69 | 4.69 |
| 505.71 | 5.87 | 5.87 |
| 560.67 | 5.92 | 5.92 |
| 512.62 | 5.20 | 5.20 |
| 537.71 | 4.70 | 4.70 |
| 559.72 | 4.43 | 4.43 |
| 452.61 | 3.52 | 3.52 |
| 564.74 | 4.65 | 4.65 |
| 493.66 | 4.30 | 4.30 |
| 505.71 | 5.35 | 5.35 |
| 561.66 | 5.32 | 5.32 |
| 358.49 | 2.96 | 2.96 |
| 563.71 | 4.23 | 4.23 |
| 416.57 | 3.24 | 3.24 |
| 605.79 | 4.37 | 4.37 |
| 507.69 | 4.61 | 4.61 |
| 526.73 | 3.38 | 3.38 |
| 496.66 | 3.64 | 3.64 |
| 481.69 | 4.37 | 4.37 |
| 507.69 | 4.69 | 4.69 |
| 528.10 | 4.95 | 4.95 |
| 606.82 | 4.19 | 4.19 |
| 510.69 | 4.24 | 4.24 |
| 523.68 | 4.31 | 4.31 |
| 462.62 | 4.32 | 4.32 |
| 537.71 | 4.70 | 4.70 |
| 465.04 | 4.66 | 4.66 |
| 507.69 | 4.61 | 4.61 |
| 442.65 | 5.12 | 5.12 |
| 524.67 | 3.70 | 3.70 |
| 456.68 | 5.51 | 5.51 |
| 478.67 | 3.40 | 3.40 |
| 470.66 | 4.45 | 4.45 |
| 343.48 | 3.80 | 3.80 |
| 585.78 | 4.27 | 4.27 |
| 541.67 | 4.44 | 4.44 |
| 397.45 | 4.56 | 4.56 |
| 507.69 | 4.61 | 4.61 |
| 477.66 | 5.06 | 5.06 |
| 385.56 | 5.31 | 5.31 |
| 531.75 | 6.32 | 6.32 |
| 398.56 | 3.75 | 3.75 |
| 519.70 | 5.25 | 5.25 |
| 540.74 | 4.83 | 4.83 |
| 442.65 | 5.12 | 5.12 |
| 487.65 | 2.42 | 2.42 |
| 409.54 | 4.03 | 4.03 |
| 570.76 | 4.31 | 4.31 |
| 618.83 | 4.29 | 4.29 |
| 524.68 | 6.53 | 6.53 |
| 529.64 | 4.58 | 4.58 |
| 486.66 | 4.27 | 4.27 |
| 561.65 | 5.32 | 5.32 |
| 441.58 | 3.11 | 3.11 |
| 496.66 | 3.64 | 3.64 |
| 477.66 | 5.06 | 5.06 |
| 538.14 | 3.07 | 3.07 |
| 539.17 | 6.61 | 6.61 |
| 585.78 | 4.27 | 4.27 |
| 482.64 | 3.63 | 3.63 |
| 523.68 | 4.31 | 4.31 |
| 527.12 | 5.56 | 5.56 |
| 493.68 | 3.37 | 3.37 |
| 415.59 | 4.39 | 4.39 |
| 533.75 | 3.23 | 3.23 |
| 505.71 | 5.84 | 5.84 |
| 553.71 | 4.31 | 4.31 |
| 532.70 | 4.78 | 4.78 |
| 506.70 | 5.67 | 5.67 |
| 521.71 | 5.25 | 5.25 |
| 406.54 | 4.69 | 4.69 |
| 526.66 | 4.75 | 4.75 |
| 446.60 | 2.73 | 2.73 |
| 397.45 | 4.73 | 4.73 |
| 546.72 | 4.79 | 4.79 |
| 573.75 | 4.89 | 4.89 |
| 343.48 | 4.02 | 4.02 |
| 509.66 | 4.00 | 4.00 |
| 480.62 | 4.04 | 4.04 |
| 426.61 | 4.70 | 4.70 |
| 578.76 | 4.13 | 4.13 |
| 545.78 | 6.71 | 6.71 |
| 479.47 | 4.76 | 4.76 |
| 477.66 | 5.06 | 5.06 |
| 508.67 | 3.88 | 3.88 |
| 511.65 | 4.44 | 4.44 |
| 442.65 | 5.34 | 5.34 |
| 462.62 | 4.32 | 4.32 |
| 521.71 | 5.25 | 5.25 |
| 471.45 | 3.84 | 3.84 |
| 414.60 | 4.39 | 4.39 |
| 444.63 | 4.05 | 4.05 |
| 398.56 | 3.75 | 3.75 |
| 568.73 | 3.66 | 3.66 |
| 480.66 | 4.49 | 4.49 |
| 426.61 | 4.64 | 4.64 |
| 428.63 | 4.95 | 4.95 |
| 544.75 | 4.65 | 4.65 |
| 551.74 | 5.08 | 5.08 |
| 529.64 | 4.58 | 4.58 |
| 469.05 | 4.53 | 4.53 |
| 509.73 | 5.54 | 5.54 |
| 506.70 | 5.67 | 5.67 |
| 521.71 | 5.25 | 5.25 |
| 456.68 | 5.51 | 5.51 |
| 481.04 | 3.15 | 3.15 |
| 516.74 | 6.18 | 6.18 |
| 521.71 | 5.25 | 5.25 |
| 516.69 | 3.79 | 3.79 |
| 533.72 | 5.62 | 5.62 |
| 518.67 | 4.17 | 4.17 |
| 510.69 | 3.94 | 3.94 |
| 477.66 | 5.63 | 5.63 |
| 508.74 | 6.15 | 6.15 |
| 517.68 | 4.77 | 4.77 |
| 507.69 | 4.98 | 4.98 |
| 526.65 | 5.37 | 5.37 |
| 552.72 | 4.92 | 4.92 |
| 508.67 | 3.88 | 3.88 |
| 563.75 | 4.60 | 4.60 |
| 606.05 | 3.73 | 3.73 |
| 416.57 | 3.70 | 3.70 |
| 444.63 | 4.18 | 4.18 |
| 556.80 | 7.16 | 7.16 |
| 518.67 | 4.17 | 4.17 |
| 504.67 | 5.90 | 5.90 |
| 484.57 | 4.25 | 4.25 |
| 518.67 | 4.17 | 4.17 |
| 518.67 | 4.17 | 4.17 |
| 482.60 | 5.41 | 5.41 |
| 496.66 | 3.93 | 3.93 |
| 528.65 | 5.18 | 5.18 |
| 482.60 | 5.41 | 5.41 |
| 559.78 | 4.05 | 4.05 |
| 480.66 | 4.40 | 4.40 |
| 474.65 | 3.59 | 3.59 |
| 535.74 | 5.21 | 5.21 |
| 552.72 | 4.92 | 4.92 |
| 496.66 | 3.93 | 3.93 |
| 576.67 | 4.90 | 4.90 |
| 490.70 | 5.91 | 5.91 |
| 491.69 | 5.45 | 5.45 |
| 448.59 | 3.94 | 3.94 |
| 546.72 | 4.79 | 4.79 |
| 794.99 | 4.81 | 4.81 |
| 385.56 | 5.31 | 5.31 |
| 493.50 | 5.15 | 5.15 |
| 494.69 | 4.42 | 4.42 |
| 497.69 | 3.61 | 3.61 |
| 554.76 | 5.07 | 5.07 |
| 521.71 | 5.25 | 5.25 |
| 480.66 | 4.63 | 4.63 |
| 457.63 | 3.96 | 3.96 |
| 507.69 | 4.86 | 4.86 |
| 544.71 | 5.41 | 5.41 |
| 551.69 | 4.08 | 4.08 |
| 511.65 | 4.44 | 4.44 |
| 528.10 | 4.95 | 4.95 |
| 508.67 | 3.88 | 3.88 |
| 567.74 | 4.32 | 4.32 |
| 561.66 | 5.32 | 5.32 |
| 579.75 | 3.53 | 3.53 |
| 492.67 | 4.90 | 4.90 |
| 521.71 | 5.25 | 5.25 |
| 595.71 | 5.04 | 5.04 |
| 454.67 | 5.26 | 5.26 |
| 512.62 | 5.20 | 5.20 |
| 446.67 | 4.72 | 4.72 |
| 533.68 | 3.94 | 3.94 |
| 561.66 | 5.32 | 5.32 |
| 487.65 | 3.05 | 3.05 |
| 482.72 | 6.04 | 6.04 |
| 494.69 | 4.71 | 4.71 |
| 577.78 | 3.71 | 3.71 |
| 585.78 | 4.27 | 4.27 |
| 507.69 | 4.61 | 4.61 |
| 470.71 | 5.85 | 5.85 |
| 507.69 | 4.61 | 4.61 |
| 579.75 | 3.53 | 3.53 |
| 606.82 | 4.19 | 4.19 |
| 521.71 | 5.25 | 5.25 |
| 444.63 | 4.18 | 4.18 |
| 526.73 | 5.83 | 5.83 |
| 510.69 | 4.24 | 4.24 |
| 415.54 | 4.48 | 4.48 |
| 572.76 | 5.15 | 5.15 |
| 508.67 | 4.61 | 4.61 |
| 494.65 | 3.69 | 3.69 |
| 432.59 | 4.53 | 4.53 |
| 444.63 | 4.18 | 4.18 |
| 444.63 | 4.18 | 4.18 |
| 578.76 | 4.13 | 4.13 |
| 385.56 | 5.31 | 5.31 |
| 519.70 | 5.25 | 5.25 |
| 424.60 | 4.00 | 4.00 |
| 611.81 | 4.34 | 4.34 |
| 505.71 | 6.01 | 6.01 |
| 478.67 | 3.40 | 3.40 |
| 521.71 | 5.25 | 5.25 |
| 456.68 | 5.51 | 5.51 |
| 537.71 | 4.61 | 4.61 |
| 519.52 | 3.24 | 3.24 |
| 485.68 | 3.84 | 3.84 |
| 509.68 | 2.61 | 2.61 |
| 430.60 | 4.01 | 4.01 |
| 532.70 | 4.78 | 4.78 |
| 442.65 | 5.00 | 5.00 |
| 481.69 | 4.37 | 4.37 |
| 442.65 | 5.34 | 5.34 |
| 428.63 | 4.95 | 4.95 |
| 543.72 | 5.45 | 5.45 |
| 549.72 | 4.86 | 4.86 |
| 343.48 | 3.65 | 3.65 |
| 343.48 | 4.19 | 4.19 |
| 507.69 | 4.61 | 4.61 |
| 523.68 | 4.31 | 4.31 |
| 585.78 | 3.81 | 3.81 |
| 537.71 | 4.61 | 4.61 |
| 524.72 | 4.59 | 4.59 |
| 498.60 | 4.64 | 4.64 |
| 434.56 | 3.37 | 3.37 |
| 477.66 | 5.06 | 5.06 |
| 428.63 | 4.68 | 4.68 |
| 524.72 | 4.25 | 4.25 |
| 551.74 | 5.08 | 5.08 |
| 470.66 | 4.50 | 4.50 |
| 561.66 | 5.32 | 5.32 |
| 474.67 | 5.65 | 5.65 |
| 524.72 | 4.68 | 4.68 |
| 462.62 | 4.32 | 4.32 |
| 442.65 | 5.07 | 5.07 |
| 482.64 | 3.63 | 3.63 |
| 414.60 | 4.39 | 4.39 |
| 543.72 | 5.45 | 5.45 |
| 561.66 | 5.32 | 5.32 |
| 432.59 | 4.53 | 4.53 |
| 476.67 | 5.66 | 5.66 |
| 438.58 | 3.51 | 3.51 |
| 588.83 | 3.89 | 3.89 |
| 505.71 | 5.68 | 5.68 |
| 347.44 | 3.77 | 3.77 |
| 541.67 | 4.44 | 4.44 |
| 611.82 | 4.34 | 4.34 |
| 448.59 | 3.76 | 3.76 |
| 506.70 | 6.24 | 6.24 |
| 532.76 | 4.71 | 4.71 |
| 521.71 | 5.25 | 5.25 |
| 440.64 | 4.87 | 4.87 |
| 722.93 | 3.64 | 3.64 |
| 577.78 | 3.71 | 3.71 |
| 559.72 | 4.74 | 4.74 |
| 430.60 | 3.80 | 3.80 |
| 496.66 | 3.73 | 3.73 |
| 414.56 | 3.53 | 3.53 |
| 571.75 | 3.55 | 3.55 |
| 409.54 | 4.03 | 4.03 |
| 532.70 | 4.78 | 4.78 |
| 398.56 | 3.75 | 3.75 |
| 521.71 | 5.25 | 5.25 |
| 561.73 | 5.39 | 5.39 |
| 467.66 | 3.59 | 3.59 |
| 496.66 | 3.93 | 3.93 |
| 480.66 | 4.49 | 4.49 |
| 372.52 | 3.22 | 3.22 |
| 387.49 | 3.42 | 3.42 |
| 605.79 | 4.37 | 4.37 |
| 414.60 | 4.39 | 4.39 |
| 511.65 | 4.44 | 4.44 |
| 428.58 | 3.33 | 3.33 |
| 524.67 | 3.70 | 3.70 |
| 498.60 | 4.64 | 4.64 |
| 509.66 | 4.00 | 4.00 |
| 485.68 | 3.83 | 3.83 |
| 567.74 | 4.32 | 4.32 |
| 523.68 | 4.31 | 4.31 |
| 511.65 | 4.44 | 4.44 |
| 357.50 | 4.58 | 4.58 |
| 343.48 | 4.19 | 4.19 |
| 460.58 | 2.96 | 2.96 |
| 523.68 | 4.31 | 4.31 |
| 357.50 | 4.36 | 4.36 |
| 521.71 | 5.25 | 5.25 |
| 434.56 | 3.37 | 3.37 |
| 523.68 | 4.31 | 4.31 |
| 524.72 | 4.68 | 4.68 |
| 458.65 | 4.36 | 4.36 |
| 347.44 | 4.10 | 4.10 |
| 496.66 | 3.93 | 3.93 |
| 400.57 | 4.00 | 4.00 |
| 531.71 | 5.38 | 5.38 |
| 416.53 | 2.67 | 2.67 |
| 533.68 | 3.94 | 3.94 |
| 564.74 | 4.65 | 4.65 |
| 468.61 | 3.18 | 3.18 |
| 480.66 | 4.40 | 4.40 |
| 467.62 | 3.58 | 3.58 |
| 509.66 | 3.27 | 3.27 |
| 472.68 | 4.96 | 4.96 |
| 511.65 | 4.44 | 4.44 |
| 547.71 | 4.40 | 4.40 |
| 482.68 | 4.80 | 4.80 |
| 570.76 | 4.31 | 4.31 |
| 425.58 | 3.87 | 3.87 |
| 511.65 | 4.44 | 4.44 |
| 456.68 | 5.46 | 5.46 |
| 508.67 | 3.88 | 3.88 |
| 512.62 | 5.20 | 5.20 |
| 471.72 | 5.65 | 5.65 |
| 458.61 | 4.12 | 4.12 |
| 511.65 | 4.44 | 4.44 |
| 501.08 | 4.84 | 4.84 |
| 496.66 | 3.64 | 3.64 |
| 471.65 | 3.70 | 3.70 |
| 543.72 | 5.45 | 5.45 |