ID: ALA4477002
Type: Functional
Description: Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay
Organism: Homo sapiens
Cell type: CCD-18Co
Bioactivity
Activity Types for Assay ALA4477002
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
376.84 | 3.05 | 3.05 |
523.08 | 3.98 | 3.98 |
449.94 | 4.39 | 4.39 |
474.95 | 4.52 | 4.52 |
463.97 | 4.44 | 4.44 |
551.87 | 5.49 | 5.49 |
491.01 | 3.68 | 3.68 |
473.96 | 4.17 | 4.17 |
487.86 | 4.24 | 4.24 |
431.92 | 2.88 | 2.88 |
451.94 | 2.15 | 2.15 |
465.96 | 2.58 | 2.58 |
469.97 | 4.71 | 4.71 |
360.85 | 3.07 | 3.07 |
494.02 | 2.99 | 2.99 |
494.92 | 4.63 | 4.63 |
364.41 | 2.73 | 2.73 |
430.89 | 3.56 | 3.56 |
493.03 | 3.97 | 3.97 |
541.07 | 4.76 | 4.76 |
436.34 | 2.43 | 2.43 |
481.88 | 3.59 | 3.59 |
415.93 | 3.64 | 3.64 |
443.14 | 3.82 | 3.82 |
457.02 | 5.42 | 5.42 |
472.97 | 4.78 | 4.78 |
494.02 | 3.04 | 3.04 |
487.39 | 4.50 | 4.50 |
360.80 | 2.57 | 2.57 |
414.89 | 3.39 | 3.39 |
441.96 | 4.80 | 4.80 |
480.98 | 2.00 | 2.00 |
445.78 | 3.21 | 3.21 |
464.98 | 3.14 | 3.14 |
414.94 | 4.20 | 4.20 |
484.04 | 4.28 | 4.28 |
444.92 | 3.95 | 3.95 |
589.49 | 3.79 | 3.79 |
474.95 | 4.27 | 4.27 |
431.93 | 1.85 | 1.85 |
478.00 | 5.90 | 5.90 |
430.94 | 4.20 | 4.20 |
465.95 | 3.37 | 3.37 |
480.95 | 3.39 | 3.39 |
416.91 | 3.42 | 3.42 |
473.96 | 4.17 | 4.17 |
479.00 | 3.53 | 3.53 |
478.38 | 3.13 | 3.13 |
418.29 | 3.35 | 3.35 |
371.87 | 4.14 | 4.14 |
427.89 | 4.53 | 4.53 |
598.87 | 5.33 | 5.33 |
460.92 | 4.14 | 4.14 |
422.92 | 4.67 | 4.67 |
562.14 | 4.00 | 4.00 |
536.06 | 2.05 | 2.05 |
385.65 | 2.76 | 2.76 |
483.01 | 4.09 | 4.09 |
360.85 | 3.35 | 3.35 |
551.11 | 2.92 | 2.92 |
450.95 | 2.80 | 2.80 |
372.81 | 3.20 | 3.20 |
451.75 | 3.84 | 3.84 |
413.91 | 4.29 | 4.29 |
373.84 | 2.48 | 2.48 |
544.10 | 5.05 | 5.05 |
548.11 | 3.61 | 3.61 |
551.02 | 5.45 | 5.45 |
490.99 | 4.90 | 4.90 |
471.00 | 4.80 | 4.80 |
578.14 | 3.23 | 3.23 |
413.91 | 3.75 | 3.75 |
489.83 | 2.79 | 2.79 |
489.96 | 4.66 | 4.66 |
460.33 | 2.89 | 2.89 |
444.92 | 4.00 | 4.00 |
476.99 | 3.29 | 3.29 |
442.77 | 4.05 | 4.05 |
562.14 | 3.53 | 3.53 |
357.84 | 3.81 | 3.81 |
479.99 | 2.60 | 2.60 |
452.78 | 4.66 | 4.66 |
459.81 | 3.60 | 3.60 |
386.88 | 3.42 | 3.42 |
458.95 | 3.66 | 3.66 |
414.89 | 3.70 | 3.70 |
398.69 | 3.71 | 3.71 |
491.22 | 2.71 | 2.71 |
479.00 | 3.58 | 3.58 |
434.88 | 3.45 | 3.45 |
386.88 | 3.47 | 3.47 |
443.98 | 3.40 | 3.40 |
506.03 | 2.62 | 2.62 |
472.97 | 4.73 | 4.73 |
414.94 | 4.20 | 4.20 |
562.14 | 4.22 | 4.22 |
449.94 | 4.39 | 4.39 |
386.88 | 3.60 | 3.60 |
479.99 | 2.93 | 2.93 |
536.10 | 3.47 | 3.47 |
476.99 | 3.33 | 3.33 |
532.05 | 3.49 | 3.49 |
340.21 | 3.25 | 3.25 |
360.85 | 3.43 | 3.43 |
429.32 | 3.49 | 3.49 |
527.05 | 4.32 | 4.32 |
428.96 | 4.59 | 4.59 |
403.28 | 3.78 | 3.78 |
490.99 | 4.82 | 4.82 |
384.86 | 4.90 | 4.90 |
449.91 | 3.02 | 3.02 |
470.02 | 3.89 | 3.89 |
402.88 | 2.44 | 2.44 |
465.96 | 2.54 | 2.54 |
446.77 | 2.60 | 2.60 |
454.75 | 3.51 | 3.51 |
537.00 | 5.06 | 5.06 |
440.93 | 3.73 | 3.73 |
370.88 | 3.64 | 3.64 |
507.01 | 2.65 | 2.65 |
427.93 | 4.82 | 4.82 |
438.75 | 4.27 | 4.27 |
408.89 | 4.28 | 4.28 |
399.29 | 3.48 | 3.48 |
444.96 | 3.79 | 3.79 |
458.01 | 3.92 | 3.92 |
507.06 | 4.22 | 4.22 |
468.99 | 4.51 | 4.51 |
442.99 | 4.84 | 4.84 |
438.30 | 2.99 | 2.99 |
402.29 | 4.38 | 4.38 |
688.19 | 6.46 | 6.46 |
472.97 | 3.75 | 3.75 |
491.01 | 2.95 | 2.95 |
474.82 | 3.24 | 3.24 |
502.46 | 3.85 | 3.85 |
511.26 | 5.16 | 5.16 |
558.12 | 5.49 | 5.49 |
476.96 | 4.43 | 4.43 |
518.95 | 4.03 | 4.03 |
491.01 | 3.68 | 3.68 |
473.83 | 3.86 | 3.86 |
528.14 | 5.74 | 5.74 |
431.92 | 3.07 | 3.07 |
518.41 | 4.28 | 4.28 |
455.74 | 2.90 | 2.90 |
460.99 | 3.59 | 3.59 |
527.88 | 3.89 | 3.89 |
439.74 | 3.67 | 3.67 |
502.02 | 3.88 | 3.88 |
473.96 | 4.17 | 4.17 |
346.82 | 3.04 | 3.04 |
494.00 | 3.85 | 3.85 |
457.96 | 3.87 | 3.87 |
460.96 | 4.63 | 4.63 |
397.91 | 5.05 | 5.05 |
473.96 | 4.12 | 4.12 |
480.97 | 5.18 | 5.18 |
507.98 | 4.95 | 4.95 |
450.93 | 3.79 | 3.79 |
348.20 | 3.36 | 3.36 |
505.02 | 5.07 | 5.07 |
477.01 | 5.35 | 5.35 |
535.07 | 2.66 | 2.66 |
464.53 | 3.39 | 3.39 |
458.01 | 3.79 | 3.79 |
304.74 | 2.65 | 2.65 |
515.06 | 2.86 | 2.86 |
532.02 | 3.64 | 3.64 |
385.90 | 4.66 | 4.66 |
542.12 | 5.12 | 5.12 |
425.92 | 3.71 | 3.71 |
488.85 | 3.63 | 3.63 |
487.00 | 5.12 | 5.12 |
472.97 | 3.75 | 3.75 |
370.84 | 4.48 | 4.48 |
476.96 | 4.38 | 4.38 |
304.74 | 2.65 | 2.65 |
518.95 | 4.08 | 4.08 |
588.96 | 4.32 | 4.32 |
415.90 | 4.73 | 4.73 |
408.84 | 5.04 | 5.04 |
518.28 | 4.10 | 4.10 |
505.04 | 3.97 | 3.97 |
474.95 | 4.53 | 4.53 |
443.94 | 2.67 | 2.67 |
502.02 | 4.81 | 4.81 |
458.95 | 4.75 | 4.75 |
374.87 | 3.65 | 3.65 |
431.88 | 2.96 | 2.96 |
536.10 | 3.51 | 3.51 |
372.86 | 3.21 | 3.21 |
567.91 | 5.12 | 5.12 |
414.94 | 4.57 | 4.57 |
585.15 | 4.35 | 4.35 |
516.04 | 5.20 | 5.20 |
477.89 | 5.16 | 5.16 |
380.84 | 4.32 | 4.32 |
464.98 | 3.19 | 3.19 |
506.43 | 3.91 | 3.91 |
534.06 | 4.97 | 4.97 |
490.99 | 4.82 | 4.82 |
459.81 | 3.60 | 3.60 |
472.97 | 4.78 | 4.78 |
490.82 | 2.18 | 2.18 |
400.87 | 3.36 | 3.36 |
479.00 | 3.86 | 3.86 |
445.78 | 3.08 | 3.08 |
533.99 | 6.03 | 6.03 |
362.26 | 4.92 | 4.92 |
419.74 | 3.04 | 3.04 |
411.89 | 3.32 | 3.32 |
551.11 | 3.25 | 3.25 |
429.78 | 3.38 | 3.38 |
388.86 | 3.22 | 3.22 |
430.94 | 3.44 | 3.44 |
530.47 | 3.24 | 3.24 |
485.03 | 2.70 | 2.70 |
446.77 | 2.60 | 2.60 |
608.12 | 5.38 | 5.38 |
594.11 | 5.18 | 5.18 |
428.96 | 4.45 | 4.45 |
481.04 | 5.25 | 5.25 |
492.37 | 4.11 | 4.11 |
353.42 | 3.16 | 3.16 |
487.00 | 5.17 | 5.17 |
493.01 | 5.05 | 5.05 |
530.98 | 6.06 | 6.06 |
472.37 | 4.87 | 4.87 |
450.95 | 2.75 | 2.75 |
525.31 | 2.75 | 2.75 |
479.99 | 2.93 | 2.93 |
465.95 | 3.37 | 3.37 |
444.96 | 3.83 | 3.83 |
473.83 | 3.85 | 3.85 |
505.02 | 5.07 | 5.07 |
463.97 | 4.39 | 4.39 |
491.01 | 3.72 | 3.72 |
550.13 | 3.86 | 3.86 |
562.14 | 4.04 | 4.04 |
542.49 | 3.46 | 3.46 |
577.15 | 3.78 | 3.78 |
464.98 | 3.14 | 3.14 |
517.03 | 5.55 | 5.55 |
494.92 | 4.58 | 4.58 |
528.10 | 4.69 | 4.69 |
443.98 | 3.36 | 3.36 |
448.95 | 5.00 | 5.00 |
463.97 | 4.44 | 4.44 |
534.06 | 4.78 | 4.78 |
387.87 | 3.63 | 3.63 |
565.14 | 3.31 | 3.31 |
474.95 | 4.27 | 4.27 |
462.98 | 5.04 | 5.04 |
452.74 | 3.24 | 3.24 |
463.97 | 4.44 | 4.44 |
361.79 | 3.85 | 3.85 |
486.02 | 3.66 | 3.66 |
479.00 | 3.53 | 3.53 |
446.77 | 2.60 | 2.60 |
491.04 | 6.18 | 6.18 |
418.90 | 3.76 | 3.76 |
480.96 | 4.09 | 4.09 |
464.95 | 4.42 | 4.42 |
430.94 | 3.44 | 3.44 |
459.94 | 5.67 | 5.67 |
536.10 | 3.47 | 3.47 |
430.94 | 4.24 | 4.24 |
409.32 | 3.08 | 3.08 |
416.91 | 3.98 | 3.98 |
558.12 | 5.44 | 5.44 |
550.13 | 3.85 | 3.85 |
411.89 | 4.31 | 4.31 |
444.97 | 2.80 | 2.80 |
467.93 | 4.53 | 4.53 |
463.54 | 3.99 | 3.99 |
412.72 | 3.74 | 3.74 |
480.89 | 4.19 | 4.19 |
475.01 | 3.84 | 3.84 |
473.96 | 3.06 | 3.06 |
428.92 | 3.78 | 3.78 |
440.98 | 4.74 | 4.74 |
514.44 | 2.68 | 2.68 |
444.96 | 3.83 | 3.83 |
487.99 | 4.56 | 4.56 |
401.89 | 3.88 | 3.88 |
402.88 | 3.59 | 3.59 |
536.04 | 3.63 | 3.63 |
426.90 | 4.98 | 4.98 |
460.79 | 2.99 | 2.99 |
622.15 | 5.77 | 5.77 |
374.83 | 2.96 | 2.96 |
522.07 | 3.08 | 3.08 |
479.00 | 3.53 | 3.53 |