Basic Information
ID: ALA4477003
Type: Functional
Description: Cytotoxicity against human PC14 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay
Organism: Homo sapiens
Cell type: PC-14
Activity Charts
Bioactivity
Activity Types for Assay ALA4477003
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.84 | 3.05 | 3.05 |
| 523.08 | 3.98 | 3.98 |
| 449.94 | 4.39 | 4.39 |
| 474.95 | 4.52 | 4.52 |
| 463.97 | 4.44 | 4.44 |
| 551.87 | 5.49 | 5.49 |
| 491.01 | 3.68 | 3.68 |
| 487.86 | 4.24 | 4.24 |
| 431.92 | 2.88 | 2.88 |
| 451.94 | 2.15 | 2.15 |
| 465.96 | 2.58 | 2.58 |
| 469.97 | 4.71 | 4.71 |
| 360.85 | 3.07 | 3.07 |
| 494.02 | 2.99 | 2.99 |
| 494.92 | 4.63 | 4.63 |
| 430.89 | 3.56 | 3.56 |
| 493.03 | 3.97 | 3.97 |
| 541.07 | 4.76 | 4.76 |
| 481.88 | 3.59 | 3.59 |
| 415.93 | 3.64 | 3.64 |
| 443.14 | 3.82 | 3.82 |
| 457.02 | 5.42 | 5.42 |
| 472.97 | 4.78 | 4.78 |
| 494.02 | 3.04 | 3.04 |
| 487.39 | 4.50 | 4.50 |
| 360.80 | 2.57 | 2.57 |
| 414.89 | 3.39 | 3.39 |
| 480.98 | 2.00 | 2.00 |
| 445.78 | 3.21 | 3.21 |
| 464.98 | 3.14 | 3.14 |
| 484.04 | 4.28 | 4.28 |
| 474.95 | 4.27 | 4.27 |
| 431.93 | 1.85 | 1.85 |
| 478.00 | 5.90 | 5.90 |
| 430.94 | 4.20 | 4.20 |
| 465.95 | 3.37 | 3.37 |
| 480.95 | 3.39 | 3.39 |
| 479.00 | 3.53 | 3.53 |
| 478.38 | 3.13 | 3.13 |
| 418.29 | 3.35 | 3.35 |
| 598.87 | 5.33 | 5.33 |
| 460.92 | 4.14 | 4.14 |
| 562.14 | 4.00 | 4.00 |
| 536.06 | 2.05 | 2.05 |
| 483.01 | 4.09 | 4.09 |
| 360.85 | 3.35 | 3.35 |
| 551.11 | 2.92 | 2.92 |
| 450.95 | 2.80 | 2.80 |
| 372.81 | 3.20 | 3.20 |
| 451.75 | 3.84 | 3.84 |
| 373.84 | 2.48 | 2.48 |
| 544.10 | 5.05 | 5.05 |
| 548.11 | 3.61 | 3.61 |
| 551.02 | 5.45 | 5.45 |
| 490.99 | 4.90 | 4.90 |
| 471.00 | 4.80 | 4.80 |
| 578.14 | 3.23 | 3.23 |
| 413.91 | 3.75 | 3.75 |
| 489.83 | 2.79 | 2.79 |
| 489.96 | 4.66 | 4.66 |
| 460.33 | 2.89 | 2.89 |
| 444.92 | 4.00 | 4.00 |
| 476.99 | 3.29 | 3.29 |
| 562.14 | 3.53 | 3.53 |
| 357.84 | 3.81 | 3.81 |
| 479.99 | 2.60 | 2.60 |
| 459.81 | 3.60 | 3.60 |
| 458.95 | 3.66 | 3.66 |
| 414.89 | 3.70 | 3.70 |
| 398.69 | 3.71 | 3.71 |
| 479.00 | 3.58 | 3.58 |
| 386.88 | 3.47 | 3.47 |
| 443.98 | 3.40 | 3.40 |
| 506.03 | 2.62 | 2.62 |
| 472.97 | 4.73 | 4.73 |
| 562.14 | 4.22 | 4.22 |
| 449.94 | 4.39 | 4.39 |
| 479.99 | 2.93 | 2.93 |
| 536.10 | 3.47 | 3.47 |
| 476.99 | 3.33 | 3.33 |
| 532.05 | 3.49 | 3.49 |
| 340.21 | 3.25 | 3.25 |
| 429.32 | 3.49 | 3.49 |
| 527.05 | 4.32 | 4.32 |
| 428.96 | 4.59 | 4.59 |
| 403.28 | 3.78 | 3.78 |
| 490.99 | 4.82 | 4.82 |
| 449.91 | 3.02 | 3.02 |
| 470.02 | 3.89 | 3.89 |
| 402.88 | 2.44 | 2.44 |
| 465.96 | 2.54 | 2.54 |
| 454.75 | 3.51 | 3.51 |
| 537.00 | 5.06 | 5.06 |
| 440.93 | 3.73 | 3.73 |
| 370.88 | 3.64 | 3.64 |
| 507.01 | 2.65 | 2.65 |
| 438.75 | 4.27 | 4.27 |
| 458.01 | 3.92 | 3.92 |
| 507.06 | 4.22 | 4.22 |
| 468.99 | 4.51 | 4.51 |
| 442.99 | 4.84 | 4.84 |
| 688.19 | 6.46 | 6.46 |
| 472.97 | 3.75 | 3.75 |
| 491.01 | 2.95 | 2.95 |
| 502.46 | 3.85 | 3.85 |
| 558.12 | 5.49 | 5.49 |
| 476.96 | 4.43 | 4.43 |
| 518.95 | 4.03 | 4.03 |
| 491.01 | 3.68 | 3.68 |
| 473.83 | 3.86 | 3.86 |
| 528.14 | 5.74 | 5.74 |
| 431.92 | 3.07 | 3.07 |
| 460.99 | 3.59 | 3.59 |
| 439.74 | 3.67 | 3.67 |
| 502.02 | 3.88 | 3.88 |
| 494.00 | 3.85 | 3.85 |
| 457.96 | 3.87 | 3.87 |
| 397.91 | 5.05 | 5.05 |
| 473.96 | 4.12 | 4.12 |
| 480.97 | 5.18 | 5.18 |
| 507.98 | 4.95 | 4.95 |
| 450.93 | 3.79 | 3.79 |
| 505.02 | 5.07 | 5.07 |
| 477.01 | 5.35 | 5.35 |
| 535.07 | 2.66 | 2.66 |
| 458.01 | 3.79 | 3.79 |
| 515.06 | 2.86 | 2.86 |
| 532.02 | 3.64 | 3.64 |
| 385.90 | 4.66 | 4.66 |
| 542.12 | 5.12 | 5.12 |
| 487.00 | 5.12 | 5.12 |
| 472.97 | 3.75 | 3.75 |
| 476.96 | 4.38 | 4.38 |
| 518.95 | 4.08 | 4.08 |
| 408.84 | 5.04 | 5.04 |
| 505.04 | 3.97 | 3.97 |
| 474.95 | 4.53 | 4.53 |
| 443.94 | 2.67 | 2.67 |
| 458.95 | 4.75 | 4.75 |
| 431.88 | 2.96 | 2.96 |
| 536.10 | 3.51 | 3.51 |
| 372.86 | 3.21 | 3.21 |
| 567.91 | 5.12 | 5.12 |
| 585.15 | 4.35 | 4.35 |
| 516.04 | 5.20 | 5.20 |
| 477.89 | 5.16 | 5.16 |
| 464.98 | 3.19 | 3.19 |
| 506.43 | 3.91 | 3.91 |
| 534.06 | 4.97 | 4.97 |
| 490.99 | 4.82 | 4.82 |
| 472.97 | 4.78 | 4.78 |
| 400.87 | 3.36 | 3.36 |
| 479.00 | 3.86 | 3.86 |
| 533.99 | 6.03 | 6.03 |
| 362.26 | 4.92 | 4.92 |
| 411.89 | 3.32 | 3.32 |
| 551.11 | 3.25 | 3.25 |
| 429.78 | 3.38 | 3.38 |
| 530.47 | 3.24 | 3.24 |
| 485.03 | 2.70 | 2.70 |
| 608.12 | 5.38 | 5.38 |
| 594.11 | 5.18 | 5.18 |
| 428.96 | 4.45 | 4.45 |
| 481.04 | 5.25 | 5.25 |
| 493.01 | 5.05 | 5.05 |
| 530.98 | 6.06 | 6.06 |
| 472.37 | 4.87 | 4.87 |
| 450.95 | 2.75 | 2.75 |
| 479.99 | 2.93 | 2.93 |
| 465.95 | 3.37 | 3.37 |
| 505.02 | 5.07 | 5.07 |
| 463.97 | 4.39 | 4.39 |
| 491.01 | 3.72 | 3.72 |
| 550.13 | 3.86 | 3.86 |
| 562.14 | 4.04 | 4.04 |
| 542.49 | 3.46 | 3.46 |
| 577.15 | 3.78 | 3.78 |
| 464.98 | 3.14 | 3.14 |
| 517.03 | 5.55 | 5.55 |
| 494.92 | 4.58 | 4.58 |
| 528.10 | 4.69 | 4.69 |
| 443.98 | 3.36 | 3.36 |
| 448.95 | 5.00 | 5.00 |
| 463.97 | 4.44 | 4.44 |
| 534.06 | 4.78 | 4.78 |
| 387.87 | 3.63 | 3.63 |
| 565.14 | 3.31 | 3.31 |
| 474.95 | 4.27 | 4.27 |
| 462.98 | 5.04 | 5.04 |
| 452.74 | 3.24 | 3.24 |
| 463.97 | 4.44 | 4.44 |
| 361.79 | 3.85 | 3.85 |
| 486.02 | 3.66 | 3.66 |
| 479.00 | 3.53 | 3.53 |
| 491.04 | 6.18 | 6.18 |
| 418.90 | 3.76 | 3.76 |
| 480.96 | 4.09 | 4.09 |
| 464.95 | 4.42 | 4.42 |
| 459.94 | 5.67 | 5.67 |
| 536.10 | 3.47 | 3.47 |
| 430.94 | 4.24 | 4.24 |
| 416.91 | 3.98 | 3.98 |
| 558.12 | 5.44 | 5.44 |
| 550.13 | 3.85 | 3.85 |
| 444.97 | 2.80 | 2.80 |
| 467.93 | 4.53 | 4.53 |
| 463.54 | 3.99 | 3.99 |
| 412.72 | 3.74 | 3.74 |
| 480.89 | 4.19 | 4.19 |
| 475.01 | 3.84 | 3.84 |
| 473.96 | 3.06 | 3.06 |
| 428.92 | 3.78 | 3.78 |
| 440.98 | 4.74 | 4.74 |
| 514.44 | 2.68 | 2.68 |
| 444.96 | 3.83 | 3.83 |
| 401.89 | 3.88 | 3.88 |
| 402.88 | 3.59 | 3.59 |
| 536.04 | 3.63 | 3.63 |
| 622.15 | 5.77 | 5.77 |
| 374.83 | 2.96 | 2.96 |
| 522.07 | 3.08 | 3.08 |
| 479.00 | 3.53 | 3.53 |