Basic Information
ID: ALA4477128
Type: Binding
Description: Inhibition of human CH24H expressed in Freestyle-293 cells assessed as reduction in 24HC production at 1 uM incubated for 5 hrs using [14C]cholesterol as substrate relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4477128
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.47 | 2.04 | 2.04 |
| 401.94 | 3.78 | 3.78 |
| 324.39 | 1.44 | 1.44 |
| 372.42 | 3.23 | 3.23 |
| 400.43 | 2.55 | 2.55 |
| 408.48 | 3.09 | 3.09 |
| 383.50 | 2.43 | 2.43 |
| 297.36 | 1.60 | 1.60 |
| 408.27 | 2.43 | 2.43 |
| 389.89 | 2.38 | 2.38 |
| 400.48 | 2.73 | 2.73 |
| 401.54 | 2.76 | 2.76 |
| 384.45 | 2.75 | 2.75 |
| 420.85 | 2.90 | 2.90 |
| 357.43 | 2.36 | 2.36 |
| 416.50 | 4.58 | 4.58 |
| 403.91 | 2.77 | 2.77 |
| 333.44 | 3.34 | 3.34 |
| 357.43 | 2.36 | 2.36 |
| 401.49 | 2.38 | 2.38 |
| 398.48 | 3.14 | 3.14 |
| 372.42 | 3.07 | 3.07 |
| 343.41 | 1.97 | 1.97 |
| 389.89 | 2.29 | 2.29 |
| 325.42 | 2.02 | 2.02 |
| 373.46 | 3.18 | 3.18 |
| 378.27 | 2.33 | 2.33 |
| 382.47 | 1.27 | 1.27 |
| 313.41 | 1.88 | 1.88 |
| 423.93 | 1.39 | 1.39 |
| 325.39 | 2.95 | 2.95 |
| 382.49 | 2.64 | 2.64 |
| 381.51 | 3.24 | 3.24 |
| 372.42 | 3.07 | 3.07 |
| 339.44 | 2.45 | 2.45 |
| 440.50 | 3.43 | 3.43 |
| 409.87 | 3.44 | 3.44 |
| 383.88 | 3.65 | 3.65 |
| 400.43 | 2.55 | 2.55 |
| 396.52 | 3.03 | 3.03 |
| 411.51 | 3.84 | 3.84 |
| 364.45 | 2.31 | 2.31 |
| 384.45 | 2.75 | 2.75 |
| 401.49 | 2.38 | 2.38 |
| 394.48 | 1.93 | 1.93 |
| 314.39 | 2.35 | 2.35 |
| 361.45 | 3.43 | 3.43 |
| 360.46 | 2.91 | 2.91 |
| 389.89 | 2.43 | 2.43 |
| 336.44 | 2.98 | 2.98 |
| 397.43 | 3.12 | 3.12 |
| 419.50 | 3.86 | 3.86 |
| 388.47 | 3.99 | 3.99 |
| 322.41 | 2.74 | 2.74 |
| 366.49 | 3.66 | 3.66 |
| 387.49 | 3.52 | 3.52 |
| 369.47 | 2.04 | 2.04 |
| 358.39 | 2.68 | 2.68 |
| 384.45 | 2.75 | 2.75 |
| 418.47 | 2.88 | 2.88 |
| 339.44 | 2.38 | 2.38 |
| 322.41 | 2.64 | 2.64 |
| 339.44 | 2.41 | 2.41 |
| 359.86 | 2.76 | 2.76 |
| 389.89 | 2.38 | 2.38 |
| 374.45 | 2.57 | 2.57 |
| 387.87 | 2.14 | 2.14 |
| 394.48 | 1.93 | 1.93 |
| 361.45 | 2.87 | 2.87 |
| 363.82 | 2.32 | 2.32 |
| 369.47 | 2.04 | 2.04 |
| 390.49 | 2.88 | 2.88 |
| 377.85 | 2.71 | 2.71 |
| 340.40 | 2.73 | 2.73 |
| 382.47 | 1.27 | 1.27 |
| 415.51 | 2.77 | 2.77 |
| 438.87 | 1.86 | 1.86 |
| 422.30 | 2.82 | 2.82 |
| 384.45 | 2.75 | 2.75 |
| 349.48 | 3.55 | 3.55 |
| 389.89 | 2.38 | 2.38 |
| 333.82 | 2.23 | 2.23 |
| 339.44 | 2.41 | 2.41 |
| 311.39 | 2.00 | 2.00 |
| 340.40 | 2.78 | 2.78 |
| 378.48 | 2.70 | 2.70 |
| 374.44 | 3.60 | 3.60 |
| 369.44 | 2.54 | 2.54 |
| 354.43 | 3.12 | 3.12 |
| 353.35 | 2.25 | 2.25 |
| 425.87 | 2.68 | 2.68 |
| 389.89 | 2.38 | 2.38 |
| 374.49 | 3.30 | 3.30 |
| 369.47 | 2.04 | 2.04 |
| 377.85 | 2.71 | 2.71 |
| 358.39 | 2.84 | 2.84 |
| 373.89 | 3.15 | 3.15 |
| 307.40 | 2.81 | 2.81 |
| 387.92 | 3.54 | 3.54 |
| 380.43 | 2.51 | 2.51 |
| 383.47 | 2.93 | 2.93 |
| 321.42 | 3.24 | 3.24 |