Basic Information
ID: ALA4477141
Type: Binding
Description: Inhibition of recombinant human TLL1 I156V/N221S/V284A mutant expressed in CHOE1A cells pre-incubated for 10 mins before promyostatin peptide substrate addition and measured after 60 mins by FRET based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4477141
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 541.65 | 4.01 | 4.01 |
| 491.51 | 4.22 | 4.22 |
| 657.72 | 2.36 | 2.36 |
| 455.51 | 2.90 | 2.90 |
| 563.59 | 3.18 | 3.18 |
| 459.52 | 3.35 | 3.35 |
| 680.16 | 2.38 | 2.38 |
| 429.52 | 2.42 | 2.42 |
| 542.63 | 3.40 | 3.40 |
| 642.58 | 2.77 | 2.77 |
| 528.61 | 3.47 | 3.47 |
| 524.62 | 3.49 | 3.49 |
| 441.53 | 3.21 | 3.21 |
| 460.51 | 2.74 | 2.74 |
| 667.65 | 2.64 | 2.64 |
| 446.51 | 2.65 | 2.65 |
| 544.61 | 3.18 | 3.18 |
| 529.59 | 2.87 | 2.87 |
| 529.59 | 2.87 | 2.87 |
| 453.54 | 3.21 | 3.21 |
| 650.54 | 1.88 | 1.88 |
| 473.53 | 2.01 | 2.01 |
| 527.62 | 4.08 | 4.08 |
| 499.56 | 3.38 | 3.38 |
| 429.49 | 3.34 | 3.34 |
| 480.49 | 3.62 | 3.62 |
| 458.52 | 2.73 | 2.73 |
| 467.57 | 3.60 | 3.60 |
| 416.48 | 2.50 | 2.50 |
| 650.13 | 2.34 | 2.34 |
| 469.58 | 3.99 | 3.99 |
| 413.48 | 1.99 | 1.99 |
| 453.58 | 4.32 | 4.32 |
| 771.74 | 2.82 | 2.82 |
| 673.68 | 1.50 | 1.50 |
| 451.57 | 3.76 | 3.76 |
| 459.52 | 3.35 | 3.35 |
| 427.50 | 2.91 | 2.91 |
| 471.55 | 3.22 | 3.22 |
| 412.49 | 2.60 | 2.60 |
| 477.51 | 3.49 | 3.49 |
| 429.49 | 3.34 | 3.34 |
| 454.53 | 2.30 | 2.30 |
| 563.59 | 3.18 | 3.18 |
| 504.61 | 2.57 | 2.57 |
| 443.50 | 2.00 | 2.00 |
| 454.53 | 2.60 | 2.60 |
| 491.51 | 4.22 | 4.22 |
| 642.71 | 3.04 | 3.04 |
| 643.69 | 2.43 | 2.43 |
| 672.61 | 2.54 | 2.54 |
| 442.52 | 2.60 | 2.60 |
| 453.54 | 3.21 | 3.21 |
| 441.53 | 3.21 | 3.21 |
| 643.69 | 2.43 | 2.43 |
| 565.56 | 1.97 | 1.97 |
| 514.58 | 3.08 | 3.08 |
| 636.10 | 2.03 | 2.03 |
| 502.54 | 3.21 | 3.21 |
| 591.60 | 2.55 | 2.55 |
| 727.69 | 2.42 | 2.42 |
| 480.49 | 3.62 | 3.62 |
| 563.63 | 1.72 | 1.72 |
| 443.50 | 2.00 | 2.00 |
| 490.58 | 1.85 | 1.85 |
| 757.72 | 2.38 | 2.38 |
| 498.58 | 3.38 | 3.38 |
| 483.57 | 3.68 | 3.68 |
| 416.48 | 2.50 | 2.50 |
| 526.63 | 3.74 | 3.74 |
| 460.51 | 2.74 | 2.74 |
| 577.70 | 2.56 | 2.56 |
| 413.48 | 1.99 | 1.99 |
| 565.56 | 1.97 | 1.97 |
| 500.55 | 2.69 | 2.69 |
| 442.52 | 2.60 | 2.60 |
| 651.69 | 2.17 | 2.17 |
| 403.44 | 0.71 | 0.71 |
| 564.58 | 2.58 | 2.58 |
| 454.57 | 3.27 | 3.27 |
| 430.51 | 2.81 | 2.81 |
| 454.57 | 3.27 | 3.27 |
| 528.61 | 3.47 | 3.47 |
| 459.52 | 3.35 | 3.35 |
| 645.49 | 2.58 | 2.58 |
| 430.48 | 2.74 | 2.74 |
| 507.55 | 2.06 | 2.06 |
| 577.58 | 2.24 | 2.24 |
| 498.58 | 3.00 | 3.00 |
| 509.53 | 4.14 | 4.14 |
| 498.58 | 3.38 | 3.38 |
| 593.57 | 1.95 | 1.95 |
| 471.62 | 4.27 | 4.27 |
| 634.09 | 2.69 | 2.69 |
| 423.51 | 3.20 | 3.20 |
| 411.50 | 3.20 | 3.20 |
| 713.66 | 2.03 | 2.03 |
| 507.51 | 4.10 | 4.10 |
| 546.60 | 3.61 | 3.61 |
| 563.67 | 3.63 | 3.63 |
| 672.69 | 2.10 | 2.10 |
| 415.49 | 2.03 | 2.03 |
| 496.49 | 3.49 | 3.49 |
| 527.62 | 4.08 | 4.08 |
| 430.48 | 2.74 | 2.74 |
| 439.51 | 2.91 | 2.91 |
| 448.52 | 3.07 | 3.07 |
| 413.48 | 1.99 | 1.99 |
| 483.57 | 3.22 | 3.22 |
| 505.56 | 4.27 | 4.27 |
| 448.47 | 2.87 | 2.87 |
| 489.59 | 2.60 | 2.60 |
| 489.34 | ||
| 642.71 | 3.04 | 3.04 |
| 429.49 | 3.34 | 3.34 |
| 439.51 | 3.33 | 3.33 |