Basic Information
ID: ALA4477400
Type: Binding
Description: Inhibition of human microsomal 11beta-HSD1 overexpressed in HEK293 cells using [3H]-cortisone as substrate assessed as formation of [3H]-cortisol using [3H]cortisone by scintillation proximity assay in presence of NADPH
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4477400
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.69 | 6.41 | 6.41 |
| 474.73 | 5.68 | 5.68 |
| 458.73 | 6.52 | 6.52 |
| 456.71 | 6.73 | 6.73 |
| 474.73 | 5.49 | 5.49 |
| 480.56 | 4.43 | 4.43 |