Basic Information
ID: ALA4477884
Type: Binding
Description: Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition of R1881-induced receptor activation preincubated for 30 mins followed by R1881 addition measured after 16 to 24 hrs by betalactamase reporter gene assay
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Androgen Receptor(ALA3072)
Document: ALA4477199
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition of R1881-induced receptor activation preincubated for 30 mins followed by R1881 addition measured after 16 to 24 hrs by betalactamase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4477884
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.38 | 2.88 | 2.88 |
| 464.44 | 3.99 | 3.99 |
| 389.33 | 3.22 | 3.22 |
| 452.31 | 4.40 | 4.40 |
| 448.39 | 5.08 | 5.08 |
| 457.33 | 4.24 | 4.24 |
| 468.31 | 4.28 | 4.28 |
| 496.39 | 3.64 | 3.64 |
| 477.32 | 4.27 | 4.27 |
| 468.31 | 4.28 | 4.28 |
| 416.32 | 5.48 | 5.48 |
| 461.32 | 5.38 | 5.38 |
| 441.33 | 5.35 | 5.35 |
| 500.37 | 3.80 | 3.80 |
| 461.32 | 5.38 | 5.38 |
| 500.37 | 3.80 | 3.80 |
| 448.39 | 5.08 | 5.08 |
| 416.95 | 4.61 | 4.61 |
| 522.35 | 5.66 | 5.66 |
| 468.38 | 5.11 | 5.11 |
| 427.31 | 3.39 | 3.39 |
| 461.32 | 5.38 | 5.38 |
| 468.38 | 5.11 | 5.11 |
| 468.38 | 5.11 | 5.11 |
| 480.39 | 3.76 | 3.76 |
| 468.31 | 4.28 | 4.28 |