Basic Information
ID: ALA4477886
Type: ADME
Description: Intrinsic clearance in human liver microsomes assessed per mg protein at 3 uM preincubated with compound followed by NADPH addition measured after 5 to 45 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4477199
Intrinsic clearance in human liver microsomes assessed per mg protein at 3 uM preincubated with compound followed by NADPH addition measured after 5 to 45 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4477886
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 271.40 | 3.38 | 3.38 |
| 430.38 | 2.88 | 2.88 |
| 448.39 | 5.08 | 5.08 |
| 448.39 | 5.08 | 5.08 |
| 477.32 | 4.27 | 4.27 |
| 448.39 | 5.08 | 5.08 |
| 448.39 | 5.08 | 5.08 |
| 468.38 | 5.11 | 5.11 |
| 468.38 | 5.11 | 5.11 |