Basic Information
ID: ALA4477899
Type: Binding
Description: Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition of R1881-induced receptor activation at 1000 nM preincubated for 30 mins followed by R1881 addition measured after 16 to 24 hrs by betalactamase reporter gene assay relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Androgen Receptor(ALA3072)
Document: ALA4477199
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition of R1881-induced receptor activation at 1000 nM preincubated for 30 mins followed by R1881 addition measured after 16 to 24 hrs by betalactamase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4477899
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.38 | 2.88 | 2.88 |
| 389.33 | 3.22 | 3.22 |
| 496.39 | 3.64 | 3.64 |
| 468.31 | 4.28 | 4.28 |
| 448.39 | 5.08 | 5.08 |