Basic Information
ID: ALA4478076
Type: Binding
Description: Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium accumulation preincubated for 5 mins followed by icilin addition by Fluo-4-AM probe-based spectrofluorimetric assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4478076
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.79 | 3.59 | 3.59 |
| 664.80 | 8.74 | 8.74 |
| 359.34 | 2.76 | 2.76 |
| 744.67 | 6.07 | 6.07 |
| 496.65 | 5.94 | 5.94 |
| 391.43 | 3.91 | 3.91 |
| 838.87 | 9.84 | 9.84 |
| 700.68 | 8.47 | 8.47 |
| 521.57 | 4.53 | 4.53 |
| 528.61 | 3.97 | 3.97 |
| 722.47 | 7.96 | 7.96 |
| 633.57 | 7.74 | 7.74 |
| 588.66 | 4.37 | 4.37 |
| 511.02 | 5.27 | 5.27 |
| 389.41 | 4.07 | 4.07 |
| 564.68 | 6.44 | 6.44 |
| 511.02 | 5.27 | 5.27 |
| 808.85 | 8.38 | 8.38 |
| 428.53 | 3.98 | 3.98 |
| 545.55 | 3.64 | 3.64 |
| 654.68 | 6.25 | 6.25 |
| 654.68 | 6.25 | 6.25 |
| 579.45 | 4.50 | 4.50 |
| 616.71 | 4.60 | 4.60 |
| 624.80 | 6.22 | 6.22 |
| 502.56 | 2.12 | 2.12 |
| 700.68 | 8.47 | 8.47 |
| 476.57 | 4.62 | 4.62 |
| 600.66 | 6.71 | 6.71 |
| 535.00 | 4.39 | 4.39 |
| 600.66 | 6.71 | 6.71 |
| 388.46 | 2.81 | 2.81 |
| 442.56 | 4.37 | 4.37 |
| 500.55 | 3.73 | 3.73 |
| 555.47 | 5.38 | 5.38 |
| 730.86 | 7.08 | 7.08 |
| 838.87 | 9.84 | 9.84 |
| 633.57 | 7.74 | 7.74 |
| 379.38 | 4.22 | 4.22 |