Basic Information
ID: ALA4478092
Type: Binding
Description: Antagonist activity at recombinant rat TRPV4 expressed in HEK293 cells assessed as inhibition of 4alphaPDD-induced intracellular calcium accumulation preincubated for 5 mins followed by 4alphaPDD addition by Fluo-4-AM probe-based spectrofluorimetric assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4478092
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.66 | 4.37 | 4.37 |
| 564.68 | 6.44 | 6.44 |
| 600.66 | 6.71 | 6.71 |
| 633.57 | 7.74 | 7.74 |