Basic Information
ID: ALA4478106
Type: Binding
Description: Inhibition of human microsomal MAO-A expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production at 10 uM using p-tyramine as substrate after 15 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Target: Monoamine oxidase A(ALA1951)
Document: ALA4477205
Inhibition of human microsomal MAO-A expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production at 10 uM using p-tyramine as substrate after 15 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4478106
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 265.27 | 3.05 | 3.05 |
| 391.16 | 3.65 | 3.65 |
| 279.30 | 3.35 | 3.35 |
| 281.27 | 2.75 | 2.75 |
| 299.71 | 3.70 | 3.70 |
| 344.16 | 3.81 | 3.81 |
| 279.30 | 3.35 | 3.35 |
| 325.75 | 4.10 | 4.10 |
| 279.30 | 3.07 | 3.07 |
| 291.31 | 3.44 | 3.44 |
| 293.32 | 3.61 | 3.61 |
| 293.32 | 3.66 | 3.66 |
| 280.28 | 2.63 | 2.63 |
| 291.31 | 3.69 | 3.69 |
| 305.33 | 3.75 | 3.75 |
| 279.30 | 3.35 | 3.35 |
| 307.35 | 3.97 | 3.97 |
| 380.40 | 4.39 | 4.39 |
| 289.29 | 3.03 | 3.03 |
| 281.27 | 2.75 | 2.75 |
| 279.30 | 3.35 | 3.35 |
| 281.27 | 2.75 | 2.75 |
| 308.34 | 3.11 | 3.11 |
| 319.36 | 4.06 | 4.06 |
| 283.26 | 3.18 | 3.18 |
| 299.71 | 3.70 | 3.70 |
| 344.16 | 3.81 | 3.81 |
| 344.16 | 3.81 | 3.81 |