Basic Information
ID: ALA4478408
Type: Binding
Description: Inhibition of VGCC in human SHSY-5Y cells assessed as reduction of K+-evoked cytosolic ca2+ at 1 uM incubated for 10 mins prior to KCl addition by Fluo-4-AM probe-based fluorescence analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4478408
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 214.31 | 3.15 | 3.15 |
| 174.25 | 2.23 | 2.23 |
| 253.14 | 2.99 | 2.99 |
| 318.46 | 4.98 | 4.98 |
| 278.40 | 4.06 | 4.06 |
| 383.33 | 5.44 | 5.44 |
| 309.25 | 4.27 | 4.27 |
| 226.32 | 2.64 | 2.64 |
| 383.76 | 5.41 | 5.41 |
| 327.52 | 4.28 | 4.28 |
| 343.27 | 4.51 | 4.51 |
| 293.21 | 3.92 | 3.92 |
| 432.45 | 5.66 | 5.66 |
| 367.58 | 5.20 | 5.20 |
| 331.26 | 4.02 | 4.02 |
| 349.32 | 5.19 | 5.19 |
| 284.45 | 4.74 | 4.74 |
| 392.39 | 4.73 | 4.73 |
| 407.35 | 4.73 | 4.73 |
| 188.27 | 2.54 | 2.54 |
| 266.39 | 3.57 | 3.57 |
| 318.89 | 4.95 | 4.95 |
| 367.29 | 3.81 | 3.81 |
| 228.34 | 3.46 | 3.46 |
| 291.19 | 3.10 | 3.10 |