Basic Information
ID: ALA4478546
Type: Binding
Description: Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FAM fluorophore/3'-TAMRA quencher)-labeled 17-mer ssDNA-oligomer substrate measured over 45 mins by FRET analysis
Organism: Influenza A virus
Strain: H1N1
Activity Charts
Bioactivity
Activity Types for Assay ALA4478546
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.11 | -0.16 | -0.16 |
| 126.11 | 0.65 | 0.65 |
| 112.08 | 0.35 | 0.35 |
| 156.09 | 0.04 | 0.04 |
| 201.22 | 1.85 | 1.85 |
| 126.11 | 0.65 | 0.65 |
| 289.29 | 1.59 | 1.59 |
| 156.14 | 0.15 | 0.15 |
| 170.12 | 0.35 | 0.35 |
| 218.21 | 1.92 | 1.92 |
| 183.16 | -0.02 | -0.02 |
| 169.18 | 0.41 | 0.41 |
| 231.25 | 1.64 | 1.64 |
| 139.15 | 0.40 | 0.40 |
| 408.85 | 3.01 | 3.01 |
| 277.25 | 1.72 | 1.72 |
| 219.22 | -0.61 | -0.61 |
| 207.27 | 2.37 | 2.37 |
| 183.21 | 0.84 | 0.84 |
| 269.26 | 1.03 | 1.03 |
| 249.24 | 2.12 | 2.12 |
| 265.70 | 2.64 | 2.64 |
| 273.29 | 1.63 | 1.63 |
| 207.27 | 2.37 | 2.37 |
| 268.28 | 1.43 | 1.43 |
| 294.33 | 0.76 | 0.76 |
| 286.33 | 1.69 | 1.69 |
| 183.16 | 0.01 | 0.01 |
| 263.22 | 2.05 | 2.05 |
| 265.70 | 2.64 | 2.64 |
| 312.32 | 2.11 | 2.11 |
| 249.24 | 2.12 | 2.12 |
| 245.23 | 1.55 | 1.55 |
| 245.23 | 1.55 | 1.55 |
| 217.22 | 1.96 | 1.96 |
| 277.32 | 3.52 | 3.52 |
| 261.28 | 1.99 | 1.99 |
| 259.26 | 1.58 | 1.58 |
| 289.29 | 1.59 | 1.59 |
| 365.39 | 3.82 | 3.82 |
| 341.33 | 1.21 | 1.21 |
| 155.15 | -0.42 | -0.42 |
| 259.26 | 1.64 | 1.64 |
| 223.27 | 1.77 | 1.77 |
| 232.24 | 1.38 | 1.38 |
| 245.23 | 1.91 | 1.91 |
| 295.29 | 3.06 | 3.06 |
| 215.25 | 1.91 | 1.91 |
| 231.25 | 1.98 | 1.98 |
| 250.30 | 1.05 | 1.05 |
| 293.32 | 3.64 | 3.64 |
| 231.25 | 1.86 | 1.86 |
| 209.25 | 1.21 | 1.21 |
| 291.35 | 3.58 | 3.58 |
| 231.25 | 1.86 | 1.86 |
| 286.35 | 0.46 | 0.46 |
| 197.23 | 1.09 | 1.09 |
| 245.28 | 1.98 | 1.98 |
| 232.24 | 1.38 | 1.38 |
| 209.24 | 1.33 | 1.33 |
| 261.28 | 1.99 | 1.99 |
| 259.26 | 1.64 | 1.64 |
| 222.29 | 1.13 | 1.13 |
| 167.21 | 1.44 | 1.44 |
| 201.22 | 1.85 | 1.85 |
| 291.28 | 1.77 | 1.77 |
| 245.23 | 1.55 | 1.55 |
| 273.29 | 2.03 | 2.03 |
| 281.29 | 0.82 | 0.82 |
| 293.32 | 3.64 | 3.64 |
| 245.23 | 1.28 | 1.28 |