Assay Report Card

Basic Information

ID: ALA4478548

Type: Binding

Description: Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Echerichia coli BL21 cells at 50 uM using single-stranded 5'-FAM fluorophore/3'-TAMRA quencher)-labeled 17-mer ssDNA-oligomer substrate measured over 45 mins by FRET analysis

Organism: Influenza A virus

Strain: H1N1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
142.11-0.16-0.16
126.110.650.65
112.080.350.35
156.090.040.04
201.221.851.85
126.110.650.65
289.291.591.59
156.140.150.15
170.120.350.35
218.211.921.92
183.16-0.02-0.02
169.180.410.41
231.251.641.64
139.150.400.40
408.853.013.01
277.251.721.72
219.22-0.61-0.61
207.272.372.37
183.210.840.84
269.261.031.03
249.242.122.12
265.702.642.64
273.291.631.63
207.272.372.37
268.281.431.43
294.330.760.76
286.331.691.69
183.160.010.01
263.222.052.05
265.702.642.64
312.322.112.11
249.242.122.12
245.231.551.55
245.231.551.55
217.221.961.96
277.323.523.52
261.281.991.99
259.261.581.58
289.291.591.59
365.393.823.82
341.331.211.21
155.15-0.42-0.42
259.261.641.64
223.271.771.77
232.241.381.38
245.231.911.91
295.293.063.06
215.251.911.91
231.251.981.98
250.301.051.05
293.323.643.64
231.251.861.86
209.251.211.21
291.353.583.58
231.251.861.86
286.350.460.46
197.231.091.09
245.281.981.98
232.241.381.38
209.241.331.33
261.281.991.99
259.261.641.64
222.291.131.13
167.211.441.44
201.221.851.85
291.281.771.77
245.231.551.55
273.292.032.03
281.290.820.82
293.323.643.64
245.231.281.28