Basic Information
ID: ALA4478550
Type: Binding
Description: Inhibition of mRNA splicing of SMN2 exon 7 in fibroblasts derived from human SMA type 1/2/3 patient assessed as increase in SMN protein level after 48 hrs by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4478550
EC1.5
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.53 | 3.39 | 3.39 |
| 496.54 | 4.40 | 4.40 |
| 429.53 | 2.56 | 2.56 |
| 388.48 | 2.38 | 2.38 |
| 379.39 | 2.36 | 2.36 |
| 374.45 | 2.00 | 2.00 |
| 360.42 | 1.76 | 1.76 |
| 375.43 | 2.56 | 2.56 |
| 392.44 | 2.21 | 2.21 |
| 389.46 | 1.77 | 1.77 |
| 375.44 | 1.46 | 1.46 |
| 374.45 | 2.07 | 2.07 |
| 416.53 | 3.53 | 3.53 |
| 402.50 | 3.14 | 3.14 |
| 400.49 | 2.96 | 2.96 |
| 378.41 | 1.87 | 1.87 |
| 428.54 | 3.30 | 3.30 |
| 393.42 | 2.70 | 2.70 |