Basic Information
ID: ALA4478592
Type: Functional
Description: Inhibition of mRNA splicing of SMN2 exon 7 in neonatal delta7 mouse harboring FVB.Cg-Tg(SMN2 delta7)4299Ahmb Tg(SMN2)-89Ahmb Smn1tm1Msd/J assessed as increase in SMN protein level in quadriceps at 1 mg/kg, ip qd administered from postnatal day 3 to postnatal day 9 measured 1 hr after last dose by HTRF assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4478592
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.53 | 3.39 | 3.39 |
| 388.48 | 2.38 | 2.38 |
| 392.44 | 2.21 | 2.21 |