Basic Information
ID: ALA4478630
Type: Functional
Description: In vivo inhibition of mRNA splicing of human SMN2 exon 7 in FVB.Cg-Tg(SMN2 delta 7 exon)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J mouse assessed as median survival time at 0.6 mg/kg/day, po bid administered on postnatal day 24 (Rvb = 14 days)
Format: BAO_0000218
Organism: Mus musculus
Target: Mus musculus(ALA375)
Document: ALA4477216
In vivo inhibition of mRNA splicing of human SMN2 exon 7 in FVB.Cg-Tg(SMN2 delta 7 exon)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J mouse assessed as median survival time at 0.6 mg/kg/day, po bid administered on postnatal day 24 (Rvb = 14 days): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4478630
MST
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.46 | 2.87 | 2.87 |
| 417.51 | 3.65 | 3.65 |