Basic Information
ID: ALA4478638
Type: Functional
Description: In vivo inhibition of mRNA splicing of human SMN2 exon 7 in FVB.Cg-Tg(SMN2 delta 7 exon)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J mouse assessed as increase in SMN protein level in brain at 0.1 mg/kg, ip qd administered on postnatal day 3 to day 9 by HTRF assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4478638
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.46 | 2.87 | 2.87 |
| 417.51 | 3.65 | 3.65 |
| 389.46 | 1.77 | 1.77 |