Basic Information
ID: ALA4478652
Type: ADME
Description: Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 10 mins by LC/MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA4477217
Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 10 mins by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4478652
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.93 | 4.19 | 4.19 |
| 526.04 | 5.03 | 5.03 |
| 468.99 | 5.07 | 5.07 |
| 469.98 | 4.46 | 4.46 |
| 485.98 | 4.15 | 4.15 |
| 484.01 | 4.65 | 4.65 |