Basic Information
ID: ALA4478653
Type: Binding
Description: Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAEG as substrate preincubated for 20 mins followed by substrate/PDK1/MAPKAPK2/DOPS/DOPC/PtdIns(3,4,5)P3 addition measured after 30 mins by Alphascreen assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Serine/threonine-protein kinase AKT(ALA4282)
Document: ALA4477217
Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAEG as substrate preincubated for 20 mins followed by substrate/PDK1/MAPKAPK2/DOPS/DOPC/PtdIns(3,4,5)P3 addition measured after 30 mins by Alphascreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4478653
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.04 | 5.03 | 5.03 |
| 468.99 | 5.07 | 5.07 |
| 469.98 | 4.46 | 4.46 |
| 484.01 | 4.65 | 4.65 |