Basic Information
ID: ALA4478715
Type: Binding
Description: Inhibition of TMP/methicillin-resistant Staphylococcus aureus recombinant DHFR F98Y/H149R double mutant expressed in Escherichia coli BL21 (DE3) cells assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition
Organism: Staphylococcus aureus
Activity Charts
Bioactivity
Activity Types for Assay ALA4478715
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 373.46 | 3.43 | 3.43 |
| 373.46 | 3.43 | 3.43 |
| 402.45 | 3.17 | 3.17 |
| 416.48 | 3.73 | 3.73 |
| 416.48 | 3.73 | 3.73 |
| 402.45 | 3.17 | 3.17 |
| 416.48 | 3.73 | 3.73 |
| 387.44 | 3.15 | 3.15 |
| 373.46 | 3.43 | 3.43 |
| 387.44 | 3.15 | 3.15 |
| 389.46 | 2.88 | 2.88 |
| 373.46 | 3.43 | 3.43 |