Basic Information
ID: ALA4478741
Type: ADME
Description: Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluorescein/7-Benzyloxyquinoline as substrate by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4478741
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.44 | 4.16 | 4.16 |
| 405.51 | 2.24 | 2.24 |
| 416.53 | 3.21 | 3.21 |
| 416.53 | 3.15 | 3.15 |
| 416.53 | 3.21 | 3.21 |
| 430.56 | 3.52 | 3.52 |
| 418.50 | 2.61 | 2.61 |
| 403.49 | 2.30 | 2.30 |
| 420.49 | 3.04 | 3.04 |
| 402.50 | 2.90 | 2.90 |
| 470.50 | 3.92 | 3.92 |