Assay Report Card

Basic Information

ID: ALA4478752

Type: Functional

Description: In vivo antimalarial activity against Plasmodium falciparum 3D70087/N9-infected erythrocytes engrafted in NOD-scid IL-2Ryc-null mouse assessed as reduction in parasitaemia at >/= 20 mg/kg administered qd through oral gavage for 4 days measured after 2 days by SYTO-16/TER119 monoclonal antibody-based flow cytometric analysis

Organism: Plasmodium falciparum

Strain: 3D70087/N9

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
416.533.153.15