Basic Information
ID: ALA4478767
Type: Binding
Description: Inhibition of JAK in human B lymphocyte cells assessed as suppression of IL4-induced STAT6 phosphorylation preincubated for 1 hr followed by IL4 addition measured after 41/2 to 5 hrs by STAT6 reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4478767
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.41 | 3.40 | 3.40 |
| 375.38 | 5.37 | 5.37 |
| 421.45 | 2.94 | 2.94 |
| 335.36 | 2.84 | 2.84 |
| 377.44 | 3.79 | 3.79 |
| 351.82 | 3.35 | 3.35 |
| 403.48 | 4.32 | 4.32 |
| 403.36 | 3.90 | 3.90 |
| 412.45 | 3.83 | 3.83 |
| 446.55 | 3.86 | 3.86 |
| 317.37 | 2.70 | 2.70 |
| 378.43 | 2.86 | 2.86 |
| 461.56 | 2.63 | 2.63 |
| 349.39 | 3.01 | 3.01 |
| 379.41 | 2.37 | 2.37 |
| 363.41 | 3.03 | 3.03 |
| 345.42 | 3.26 | 3.26 |
| 331.40 | 3.01 | 3.01 |
| 375.43 | 3.54 | 3.54 |
| 445.90 | 5.09 | 5.09 |
| 412.45 | 3.83 | 3.83 |
| 347.40 | 2.71 | 2.71 |
| 303.34 | 2.31 | 2.31 |
| 331.40 | 3.01 | 3.01 |
| 393.44 | 3.03 | 3.03 |
| 345.42 | 3.31 | 3.31 |
| 403.48 | 4.18 | 4.18 |
| 351.82 | 3.35 | 3.35 |