Basic Information
ID: ALA4478797
Type: Binding
Description: Allosteric inhibition of HCV genotype 1a NS5A infected in human W11.8 cells assessed as reduction in viral RNA replication after 4 days by ELISA
Organism: Hepatitis C virus subtype 1a
Activity Charts
Bioactivity
Activity Types for Assay ALA4478797
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.63 | 5.31 | 5.31 |
| 460.64 | 4.87 | 4.87 |
| 474.67 | 5.12 | 5.12 |
| 462.61 | 3.45 | 3.45 |
| 474.67 | 5.26 | 5.26 |
| 472.65 | 5.02 | 5.02 |
| 502.68 | 4.64 | 4.64 |
| 488.65 | 3.99 | 3.99 |
| 487.67 | 3.78 | 3.78 |
| 446.61 | 4.48 | 4.48 |
| 476.64 | 4.11 | 4.11 |
| 418.56 | 3.75 | 3.75 |
| 460.64 | 4.87 | 4.87 |
| 489.68 | 4.02 | 4.02 |
| 446.61 | 4.48 | 4.48 |
| 446.61 | 4.53 | 4.53 |
| 432.59 | 4.09 | 4.09 |
| 474.62 | 3.86 | 3.86 |
| 460.60 | 3.21 | 3.21 |
| 458.62 | 4.63 | 4.63 |