Basic Information
ID: ALA4479014
Type: ADME
Description: Drug activation in human Hep3B cells assessed as human CYP3A4-mediated drug metabolism-induced cytotoxicity measured as decrease in cell viability at 21.7 uM pre-incubated with BSO for 18 hrs followed by incubation with compound for 3 hrs in presence of NADPH measured after 24 hrs in absence of compound, CYP3A4 and NADPH by cell titer-glo luminescence assay relative to BSO alone
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4479014
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.37 | 3.33 | 3.33 |
| 418.57 | 4.59 | 4.59 |