Basic Information
ID: ALA4479425
Type: ADME
Description: Intrinsic clearance in rat liver microsomes assessed per mg of protein at 1 uM preincubated for 5 mins followed by NADPH addition measured after 5 to 30 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4477239
Intrinsic clearance in rat liver microsomes assessed per mg of protein at 1 uM preincubated for 5 mins followed by NADPH addition measured after 5 to 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4479425
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.39 | 1.67 | 1.67 |
| 373.39 | 3.52 | 3.52 |
| 421.41 | 3.12 | 3.12 |
| 430.42 | 4.03 | 4.03 |
| 438.44 | 5.48 | 5.48 |
| 391.39 | 3.66 | 3.66 |
| 373.39 | 3.52 | 3.52 |
| 444.45 | 4.29 | 4.29 |
| 463.42 | 4.85 | 4.85 |
| 430.42 | 4.03 | 4.03 |
| 373.40 | 3.52 | 3.52 |
| 388.38 | 4.32 | 4.32 |
| 445.43 | 4.72 | 4.72 |
| 430.42 | 4.03 | 4.03 |