ID: ALA4479463
Type: Binding
Description: Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as substrate (21 to 44 residues) in presence of [3H]-S-adenosylmethionine after 2 hrs by scintillation proximity assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4479463
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
569.75 | 5.09 | 5.09 |
555.73 | 4.70 | 4.70 |
513.65 | 3.83 | 3.83 |
569.75 | 5.09 | 5.09 |
511.55 | 5.58 | 5.58 |
569.75 | 5.09 | 5.09 |
595.79 | 5.31 | 5.31 |
609.82 | 6.01 | 6.01 |
569.75 | 5.09 | 5.09 |
569.75 | 5.09 | 5.09 |
555.73 | 4.75 | 4.75 |
639.89 | 6.72 | 6.72 |
627.83 | 5.06 | 5.06 |
541.70 | 4.44 | 4.44 |
567.74 | 4.63 | 4.63 |
464.61 | 3.30 | 3.30 |
583.78 | 5.65 | 5.65 |
623.85 | 6.40 | 6.40 |
464.61 | 3.66 | 3.66 |
442.56 | 5.16 | 5.16 |
527.67 | 3.81 | 3.81 |
581.77 | 5.02 | 5.02 |
583.78 | 5.26 | 5.26 |
541.70 | 4.04 | 4.04 |
443.55 | 4.56 | 4.56 |
543.67 | 3.84 | 3.84 |
545.78 | 5.25 | 5.25 |
555.73 | 4.70 | 4.70 |
597.81 | 5.87 | 5.87 |
555.73 | 4.70 | 4.70 |
583.78 | 5.33 | 5.33 |
583.78 | 5.48 | 5.48 |
460.55 | 5.30 | 5.30 |
555.73 | 4.70 | 4.70 |
569.75 | 5.26 | 5.26 |
595.79 | 5.62 | 5.62 |
623.85 | 6.09 | 6.09 |
583.78 | 5.43 | 5.43 |
510.56 | 6.18 | 6.18 |
595.79 | 5.79 | 5.79 |
609.82 | 5.70 | 5.70 |
527.67 | 3.81 | 3.81 |
449.60 | 3.96 | 3.96 |
617.80 | 5.56 | 5.56 |
450.59 | 2.91 | 2.91 |
637.87 | 6.48 | 6.48 |
528.66 | 3.53 | 3.53 |
445.36 | 4.26 | 4.26 |
527.67 | 3.81 | 3.81 |
514.63 | 3.22 | 3.22 |
603.77 | 5.80 | 5.80 |
544.66 | 2.82 | 2.82 |
461.54 | 4.70 | 4.70 |
527.67 | 3.97 | 3.97 |