Basic Information
ID: ALA4479498
Type: ADME
Description: Unbound brain to plasma concentration ratio in Sprague-Dawley rat at 0.2 to 0.25 mg/kg, iv administered as cassette dose measured 0.25 hrs post dose
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Brain/Plasma
Target: ADMET(ALA612558)
Document: ALA4477243
Unbound brain to plasma concentration ratio in Sprague-Dawley rat at 0.2 to 0.25 mg/kg, iv administered as cassette dose measured 0.25 hrs post dose: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4479498
K(p,uu,brain)
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.37 | 3.73 | 3.73 |
| 313.38 | 3.13 | 3.13 |
| 284.34 | 2.52 | 2.52 |
| 316.81 | 4.38 | 4.38 |
| 325.39 | 3.09 | 3.09 |
| 298.37 | 3.43 | 3.43 |
| 402.48 | 3.97 | 3.97 |
| 283.36 | 3.12 | 3.12 |
| 283.36 | 3.12 | 3.12 |
| 424.53 | 2.70 | 2.70 |
| 284.34 | 2.52 | 2.52 |
| 334.80 | 4.52 | 4.52 |
| 318.35 | 4.00 | 4.00 |
| 317.80 | 3.77 | 3.77 |
| 312.39 | 3.73 | 3.73 |
| 319.34 | 3.40 | 3.40 |