Basic Information
ID: ALA4479677
Type: Binding
Description: Inhibition of MARK4 in mouse cortical neurons assessed as inhibition of okadaic acid-induced tau phosphorylation at S262 residue preincubated for 15 mins followed okadaic acid challenge for 1.5 hrs by immunostaining method
Format: BAO_0000357
Organism: Mus musculus
Target: MAP/microtubule affinity-regulating kinase 4(ALA4523387)
Document: ALA4477252
Inhibition of MARK4 in mouse cortical neurons assessed as inhibition of okadaic acid-induced tau phosphorylation at S262 residue preincubated for 15 mins followed okadaic acid challenge for 1.5 hrs by immunostaining method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4479677
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.39 | 3.15 | 3.15 |
| 425.89 | 3.66 | 3.66 |
| 421.53 | 2.86 | 2.86 |
| 529.59 | 5.28 | 5.28 |