Basic Information
ID: ALA4479791
Type: Functional
Description: Positive allosteric modulation of human mGluR5A transfected in HEK293 cells assessed as potentiation of L-glutamate-induced calcium release incubated for 10 mins by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4479791
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.42 | 4.62 | 4.62 |
| 358.37 | 4.14 | 4.14 |
| 376.36 | 4.28 | 4.28 |
| 377.35 | 3.68 | 3.68 |
| 340.38 | 4.00 | 4.00 |
| 339.39 | 4.61 | 4.61 |
| 374.83 | 4.66 | 4.66 |
| 359.36 | 3.54 | 3.54 |
| 358.37 | 4.14 | 4.14 |
| 376.36 | 4.28 | 4.28 |
| 376.36 | 4.28 | 4.28 |
| 377.35 | 3.68 | 3.68 |
| 340.38 | 4.00 | 4.00 |
| 376.36 | 4.28 | 4.28 |
| 340.38 | 4.00 | 4.00 |
| 358.37 | 4.14 | 4.14 |
| 374.83 | 4.66 | 4.66 |
| 376.36 | 4.28 | 4.28 |
| 376.36 | 4.28 | 4.28 |
| 377.35 | 3.68 | 3.68 |
| 359.36 | 3.54 | 3.54 |
| 340.38 | 4.00 | 4.00 |
| 374.83 | 4.66 | 4.66 |
| 359.36 | 3.54 | 3.54 |