Assay Report Card

Basic Information

ID: ALA4479792

Type: Functional

Description: Positive allosteric modulation of human mGluR5A transfected in HEK293 cells assessed as potentiation of L-glutamate-induced calcium release incubated for 10 mins by FLIPR assay relative to control

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
369.424.624.62
358.374.144.14
376.364.284.28
377.353.683.68
374.834.664.66
359.363.543.54
358.374.144.14
376.364.284.28
376.364.284.28
377.353.683.68
340.384.004.00
376.364.284.28
340.384.004.00
358.374.144.14
376.364.284.28
377.353.683.68
359.363.543.54
340.384.004.00
374.834.664.66
359.363.543.54