Basic Information
ID: ALA4480151
Type: Binding
Description: Inhibition of NorA efflux pump overexpressed in Staphylococcus aureus 1199B assessed as fold reduction in ciprofloxacin MIC at 12.5 ug/ml measured after 24 hrs by broth checkerboard method
Organism: Staphylococcus aureus
Strain: 1199B
Activity Charts
Bioactivity
Activity Types for Assay ALA4480151
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.34 | 3.00 | 3.00 |
| 218.21 | 2.07 | 2.07 |
| 246.26 | 2.85 | 2.85 |
| 313.40 | 3.78 | 3.78 |
| 331.37 | 2.44 | 2.44 |
| 407.47 | 3.67 | 3.67 |
| 399.49 | 4.15 | 4.15 |
| 413.51 | 4.39 | 4.39 |
| 560.70 | 4.97 | 4.97 |
| 357.41 | 2.93 | 2.93 |
| 373.45 | 3.47 | 3.47 |
| 371.43 | 3.37 | 3.37 |
| 455.60 | 5.42 | 5.42 |
| 527.62 | 2.72 | 2.72 |
| 359.42 | 3.08 | 3.08 |
| 345.40 | 2.69 | 2.69 |
| 385.46 | 3.61 | 3.61 |
| 427.54 | 4.78 | 4.78 |
| 399.49 | 4.00 | 4.00 |
| 446.50 | 4.14 | 4.14 |
| 373.45 | 3.47 | 3.47 |
| 427.54 | 4.64 | 4.64 |