Basic Information
ID: ALA4480230
Type: Binding
Description: Inhibition of N-terminal His6-tagged human SETD2 (1347 to 1711 residues) expressed in Escherichia coli Rosseta-2(DE3) cells assessed as residual activity at 50 uM using biotinylated-histone H3 (20 to 50 residues) as substrate in presence of [3H-Me]SAM by scintillation proximity assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone-lysine N-methyltransferase SETD2(ALA3108647)
Document: ALA4477270
Inhibition of N-terminal His6-tagged human SETD2 (1347 to 1711 residues) expressed in Escherichia coli Rosseta-2(DE3) cells assessed as residual activity at 50 uM using biotinylated-histone H3 (20 to 50 residues) as substrate in presence of [3H-Me]SAM by scintillation proximity assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4480230
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.23 | 3.68 | 3.68 |
| 351.29 | 3.40 | 3.40 |
| 337.26 | 3.15 | 3.15 |
| 351.29 | 3.54 | 3.54 |
| 337.26 | 3.05 | 3.05 |
| 337.26 | 3.15 | 3.15 |
| 337.26 | 3.15 | 3.15 |
| 337.26 | 3.15 | 3.15 |
| 309.21 | 2.27 | 2.27 |
| 351.29 | 3.54 | 3.54 |
| 337.26 | 3.05 | 3.05 |
| 309.21 | 2.23 | 2.23 |
| 337.26 | 3.01 | 3.01 |
| 335.25 | 2.76 | 2.76 |
| 309.21 | 2.13 | 2.13 |
| 323.23 | 2.62 | 2.62 |
| 349.27 | 3.15 | 3.15 |
| 363.30 | 3.54 | 3.54 |
| 309.21 | 2.27 | 2.27 |
| 309.21 | 2.27 | 2.27 |
| 295.18 | 1.88 | 1.88 |
| 323.23 | 2.62 | 2.62 |
| 351.29 | 3.40 | 3.40 |
| 337.26 | 3.20 | 3.20 |