Assay Report Card

Basic Information

ID: ALA4480230

Type: Binding

Description: Inhibition of N-terminal His6-tagged human SETD2 (1347 to 1711 residues) expressed in Escherichia coli Rosseta-2(DE3) cells assessed as residual activity at 50 uM using biotinylated-histone H3 (20 to 50 residues) as substrate in presence of [3H-Me]SAM by scintillation proximity assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
493.233.683.68
351.293.403.40
337.263.153.15
351.293.543.54
337.263.053.05
337.263.153.15
337.263.153.15
337.263.153.15
309.212.272.27
351.293.543.54
337.263.053.05
309.212.232.23
337.263.013.01
335.252.762.76
309.212.132.13
323.232.622.62
349.273.153.15
363.303.543.54
309.212.272.27
309.212.272.27
295.181.881.88
323.232.622.62
351.293.403.40
337.263.203.20