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Inhibition of PRMT5 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scinti...

Basic Information

ID: ALA4480244

Type: Binding

Description: Inhibition of PRMT5 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control

Format: BAO_0000357

Organism: Homo sapiens

Target:  Protein arginine N-methyltransferase 5(ALA1795116)

Document:  ALA4477270

Inhibition of PRMT5 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
493.233.683.68
351.293.403.40
337.263.153.15
351.293.543.54
337.263.053.05
337.263.153.15
337.263.153.15
337.263.153.15
309.212.272.27
351.293.543.54
337.263.053.05
309.212.232.23
337.263.013.01
335.252.762.76
309.212.132.13
323.232.622.62
349.273.153.15
363.303.543.54
309.212.272.27
309.212.272.27
295.181.881.88
323.232.622.62
351.293.403.40
337.263.203.20