Basic Information
ID: ALA4480299
Type: Binding
Description: Inhibition of DOT1L in human HeLa cells assessed as reduction in H3K79me2 level after 72 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Histone-lysine N-methyltransferase, H3 lysine-79 specific(ALA1795117)
Document: ALA4477274
Inhibition of DOT1L in human HeLa cells assessed as reduction in H3K79me2 level after 72 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4480299
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 524.44 | 5.91 | 5.91 |
| 476.54 | 5.59 | 5.59 |