Basic Information
ID: ALA4480602
Type: Binding
Description: Antagonist activity at histamine H3 receptor in guinea pig jejunum assessed as effect on pyrilamine-induced inhibition of electrically evoked contraction treated 20 mins after pyrilamine stimulation and measured after 1 hr equilibration followed by compound wash out every 10 mins
Organism: Cavia porcellus
Tissue: Jejunum
Activity Charts
Bioactivity
Activity Types for Assay ALA4480602
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.16 | 5.46 | 5.46 |
| 479.71 | 4.81 | 4.81 |
| 524.71 | 4.72 | 4.72 |
| 547.71 | 5.83 | 5.83 |