Basic Information
ID: ALA4480653
Type: Binding
Description: Inhibition of beta-lactamase VIM-2 in Pseudomonas aeruginosa assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 125 uM after 20 hrs by broth microdilution assay (meropenem alone = 32 to 64 mg/L)
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA4480653
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.48 | 0.66 | 0.66 |
| 680.81 | 2.74 | 2.74 |
| 660.22 | 1.75 | 1.75 |
| 424.55 | 5.48 | 5.48 |
| 333.44 | 2.66 | 2.66 |
| 565.44 | ||
| 652.76 | 1.96 | 1.96 |
| 466.50 | -0.32 | -0.32 |
| 536.64 | 1.62 | 1.62 |
| 551.65 | 0.56 | 0.56 |
| 688.28 | 2.53 | 2.53 |
| 554.10 | 1.63 | 1.63 |
| 680.81 | 2.74 | 2.74 |
| 631.73 | 1.74 | 1.74 |
| 688.28 | 2.53 | 2.53 |
| 494.56 | 0.45 | 0.45 |
| 494.56 | 0.45 | 0.45 |
| 565.44 |