Assay Report Card

Basic Information

ID: ALA4480655

Type: Binding

Description: Inhibition of beta-lactamase VIM-2 in Pseudomonas aeruginosa assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 20 hrs by broth microdilution assay (meropenem alone = 32 to 64 mg/L)

Organism: Pseudomonas aeruginosa

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
442.523.373.37
579.660.350.35
470.570.590.59
541.661.771.77
513.610.990.99
593.690.740.74
542.601.211.21
593.690.740.74
570.651.981.98
579.660.350.35