Assay Report Card

Basic Information

ID: ALA4480659

Type: Binding

Description: Inhibition of NDM1 in Pseudomonas aeruginosa assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 31 uM after 20 hrs by broth microdilution assay (meropenem alone = 32 to 64 mg/L)

Organism: Klebsiella pneumoniae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
470.570.590.59
491.59-1.70-1.70
576.66-0.03-0.03
680.812.742.74
333.442.662.66
565.44
652.761.961.96
688.282.532.53
680.812.742.74
688.282.532.53
494.560.450.45
494.560.450.45
565.44