Basic Information
ID: ALA4480667
Type: Functional
Description: Cytoprotection against rotenone-induced mitochondrial dysfunction in human HepG2 cells assessed as increase in cell viability by measuring ATP levels at 10 uM preincubated for 48 hrs followed by rotenone-induction and measured after 24 hrs by luciferase-based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: HepG2(ALA395)
Document: ALA4480378
Cytoprotection against rotenone-induced mitochondrial dysfunction in human HepG2 cells assessed as increase in cell viability by measuring ATP levels at 10 uM preincubated for 48 hrs followed by rotenone-induction and measured after 24 hrs by luciferase-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4480667
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 3.03 | 3.03 |
| 286.33 | 3.42 | 3.42 |
| 244.25 | 2.25 | 2.25 |
| 258.27 | 2.64 | 2.64 |
| 270.37 | 4.74 | 4.74 |
| 312.45 | 5.91 | 5.91 |
| 411.50 | 3.89 | 3.89 |
| 256.34 | 4.35 | 4.35 |
| 421.49 | 3.93 | 3.93 |
| 461.56 | 4.62 | 4.62 |
| 477.56 | 4.33 | 4.33 |
| 391.47 | 3.27 | 3.27 |
| 405.45 | 3.58 | 3.58 |
| 272.30 | 2.73 | 2.73 |
| 284.40 | 5.13 | 5.13 |
| 419.48 | 3.45 | 3.45 |
| 242.27 | 2.75 | 2.75 |
| 427.54 | 4.43 | 4.43 |
| 717.82 | 7.09 | 7.09 |
| 377.44 | 3.62 | 3.62 |
| 405.45 | 3.58 | 3.58 |
| 371.43 | 3.01 | 3.01 |
| 413.51 | 4.18 | 4.18 |
| 405.45 | 3.36 | 3.36 |
| 400.48 | 4.39 | 4.39 |
| 328.45 | 4.89 | 4.89 |
| 244.29 | 2.54 | 2.54 |