Basic Information
ID: ALA4480674
Type: Binding
Description: Inhibition of NFkappaB (unknown origin) expressed in human A549 cells co-transfected with pNFkappaB-Luc vector assessed as reduction in TNFalpha-induced NFkappaB transcriptional activity co-incubated for 7 hrs in presence of TNFalpha by bright-glo luciferase reporter gene assay
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA4480674
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.71 | 5.03 | 5.03 |
| 383.68 | 5.34 | 5.34 |
| 679.35 | 6.50 | 6.50 |
| 662.89 | 5.98 | 5.98 |
| 674.93 | 5.85 | 5.85 |
| 689.90 | 5.75 | 5.75 |
| 849.91 | 8.32 | 8.32 |
| 805.46 | 8.21 | 8.21 |
| 805.46 | 8.21 | 8.21 |
| 679.35 | 6.50 | 6.50 |
| 849.91 | 8.32 | 8.32 |
| 789.00 | 7.70 | 7.70 |
| 658.93 | 6.15 | 6.15 |
| 723.80 | 6.61 | 6.61 |
| 723.80 | 6.61 | 6.61 |
| 658.93 | 6.15 | 6.15 |
| 658.93 | 6.15 | 6.15 |
| 789.00 | 7.70 | 7.70 |
| 689.90 | 5.75 | 5.75 |
| 789.00 | 7.70 | 7.70 |
| 849.91 | 8.32 | 8.32 |
| 723.80 | 6.61 | 6.61 |