Basic Information
ID: ALA4480899
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells at 10 uM using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Cyclin-dependent kinase 4/cyclin D1(ALA1907601)
Document: ALA4480390
Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells at 10 uM using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4480899
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.54 | 2.97 | 2.97 |
| 267.24 | 2.50 | 2.50 |
| 223.24 | 2.40 | 2.40 |
| 301.14 | 3.35 | 3.35 |
| 238.25 | 2.30 | 2.30 |
| 238.25 | 2.30 | 2.30 |
| 268.27 | 2.30 | 2.30 |
| 413.26 | 5.70 | 5.70 |
| 346.36 | 1.94 | 1.94 |
| 378.41 | 3.36 | 3.36 |
| 358.40 | 4.18 | 4.18 |
| 394.38 | 4.46 | 4.46 |
| 268.27 | 2.30 | 2.30 |
| 364.35 | 4.45 | 4.45 |
| 362.36 | 4.53 | 4.53 |
| 394.38 | 4.46 | 4.46 |
| 383.23 | 5.69 | 5.69 |
| 431.45 | 3.62 | 3.62 |
| 431.45 | 3.62 | 3.62 |
| 431.45 | 3.62 | 3.62 |
| 431.45 | 3.62 | 3.62 |
| 431.45 | 3.62 | 3.62 |
| 421.84 | 3.97 | 3.97 |
| 445.48 | 4.01 | 4.01 |
| 377.44 | 3.42 | 3.42 |
| 435.87 | 4.27 | 4.27 |
| 431.45 | 3.62 | 3.62 |
| 415.45 | 3.92 | 3.92 |
| 421.46 | 4.76 | 4.76 |
| 381.43 | 2.89 | 2.89 |
| 401.42 | 3.62 | 3.62 |
| 371.40 | 3.61 | 3.61 |
| 407.47 | 3.43 | 3.43 |
| 416.39 | 3.52 | 3.52 |
| 446.42 | 3.52 | 3.52 |
| 419.41 | 3.76 | 3.76 |
| 421.46 | 4.76 | 4.76 |
| 385.42 | 3.92 | 3.92 |
| 405.84 | 4.26 | 4.26 |
| 415.45 | 4.01 | 4.01 |
| 419.41 | 3.76 | 3.76 |
| 332.33 | 4.52 | 4.52 |
| 306.32 | 2.61 | 2.61 |
| 413.26 | 5.70 | 5.70 |
| 399.45 | 3.33 | 3.33 |
| 445.48 | 4.01 | 4.01 |
| 316.34 | 1.93 | 1.93 |