Basic Information
ID: ALA4480904
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Cyclin-dependent kinase 4/cyclin D1(ALA1907601)
Document: ALA4480390
Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4480904
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.54 | 2.97 | 2.97 |
| 346.36 | 1.94 | 1.94 |
| 431.45 | 3.62 | 3.62 |
| 407.47 | 3.43 | 3.43 |
| 405.84 | 4.26 | 4.26 |