Basic Information
ID: ALA4481032
Type: Binding
Description: Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 mins by human HGD coupled enzyme assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4481032
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.35 | 4.15 | 4.15 |
| 415.28 | 5.08 | 5.08 |
| 402.85 | 5.36 | 5.36 |
| 415.28 | 5.08 | 5.08 |
| 336.39 | 4.32 | 4.32 |
| 436.25 | 5.23 | 5.23 |
| 370.83 | 4.98 | 4.98 |
| 350.41 | 4.63 | 4.63 |
| 446.25 | 4.68 | 4.68 |
| 391.25 | 5.32 | 5.32 |
| 433.27 | 5.16 | 5.16 |
| 478.27 | 5.07 | 5.07 |
| 356.80 | 4.67 | 4.67 |
| 381.38 | 4.23 | 4.23 |
| 388.82 | 5.11 | 5.11 |
| 322.36 | 4.01 | 4.01 |
| 374.80 | 4.81 | 4.81 |
| 354.38 | 4.46 | 4.46 |
| 401.26 | 4.78 | 4.78 |
| 340.35 | 4.15 | 4.15 |
| 429.31 | 5.41 | 5.41 |
| 395.41 | 4.48 | 4.48 |
| 403.34 | 4.20 | 4.20 |
| 464.24 | 4.82 | 4.82 |
| 450.27 | 5.47 | 5.47 |
| 329.23 | 3.36 | 3.36 |
| 419.25 | 4.92 | 4.92 |
| 409.44 | 5.05 | 5.05 |
| 388.82 | 5.11 | 5.11 |
| 385.35 | 4.06 | 4.06 |
| 395.41 | 4.54 | 4.54 |
| 415.28 | 5.02 | 5.02 |
| 370.83 | 4.98 | 4.98 |
| 340.35 | 4.15 | 4.15 |