Basic Information
ID: ALA4481265
Type: Binding
Description: Reversible inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as recovery of transport current at IC50 followed by compound wash out followed by glycine re-application at 5 mins intervals throughout wash time course and measured after 25 mins by two-electrode voltage clamp electrophysiology
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4481265
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.10 | 5.72 | 5.72 |