Assay Report Card

Basic Information

ID: ALA4481433

Type: Functional

Description: Antimicrobial activity against adult Brugia malayi L3 larvae stage infected in CB17 SCID mouse assessed as reduction in Wolbachia load at 25 mg/kg, po administered BID for 28 days starting 6 weeks post infection and measured 12 weeks post infection by QPCR analysis relative to control

Organism: Brugia malayi

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
457.480.190.19
528.43