Basic Information
ID: ALA4481433
Type: Functional
Description: Antimicrobial activity against adult Brugia malayi L3 larvae stage infected in CB17 SCID mouse assessed as reduction in Wolbachia load at 25 mg/kg, po administered BID for 28 days starting 6 weeks post infection and measured 12 weeks post infection by QPCR analysis relative to control
Format: BAO_0000218
Organism: Brugia malayi
Target: Brugia malayi(ALA613140)
Document: ALA4480405
Antimicrobial activity against adult Brugia malayi L3 larvae stage infected in CB17 SCID mouse assessed as reduction in Wolbachia load at 25 mg/kg, po administered BID for 28 days starting 6 weeks post infection and measured 12 weeks post infection by QPCR analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4481433
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.48 | 0.19 | 0.19 |
| 528.43 |