Basic Information
ID: ALA4481484
Type: Binding
Description: Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane potential after 16 to 24 hrs by FMP-blue assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4481484
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.32 | 1.90 | 1.90 |
| 257.29 | 1.89 | 1.89 |
| 291.74 | 2.55 | 2.55 |
| 319.41 | 3.92 | 3.92 |
| 319.41 | 3.92 | 3.92 |
| 363.42 | 3.47 | 3.47 |
| 273.29 | 1.60 | 1.60 |
| 302.29 | 1.80 | 1.80 |
| 272.31 | 1.48 | 1.48 |
| 291.74 | 2.55 | 2.55 |
| 302.29 | 1.80 | 1.80 |
| 363.42 | 3.47 | 3.47 |
| 273.29 | 1.60 | 1.60 |